Velasof Tablet 400 Mg+100 Mg

Medically Reviewed by

Dr. Akanksha Kaushal

Dr. Akanksha, Pharm-D

Dr. Akansha is a licensed Clinical Pharmacologist with extensive expertise in pharmacovigilance, prescription analysis, drug information, and safety. She's a dedicated educator and avid learner. Dr. Akansha also reviews medical content on GoodRxMedicine, ensuring accurate pharmaceutical information is accessible to all.

Written by

Julian Carter

Julian Carter

Julian, an MBA in Pharmaceutical Management, brings a dynamic blend of expertise and impact with his contributions at GoodRxMedicine. His dedication and innovative spirit continue to shape a brighter future in pharmaceutical management.

What is Velasof Tablet

Velasof Tablet is an antiviral medication used to treat chronic Hepatitis C virus (HCV) infections. It contains Sofosbuvir (400 mg) and Velpatasvir (100 mg), which belong to the class of Direct-Acting Antivirals (DAAs). 

Velasof inhibits viral replication, preventing the spread of HCV in the body. This combination therapy effectively targets multiple genotypes of the Hepatitis C virus, ensuring high cure rates.

It is manufactured by Hetero Healthcare Limited in GMP-compliant facilities. 

Uses of Velasof Tablet

The uses of Velasof Tablet include:

• Treats Chronic Hepatitis C Virus (HCV) infection.
• Treating multiple HCV genotypes (1, 2, 3, 4, 5, 6).
• Reducing liver disease complications.
• Lowering the risk of liver failure.
• Combination therapy with Ribavirin in certain cases of patients with advanced liver disease.

It is a trusted therapy for patients with chronic HCV, offering a convenient, once-daily regimen. 

Working and benefits of Sofosbuvir and Velpatasvir

Velasof Tablet contains is an antiviral combination therapy that includes Sofosbuvir and Velpatasvir, which work by stopping enzymes required for viral replication. Sofosbuvir targets the NS5B RNA polymerase, blocking the virus's ability to multiply, while Velpatasvir inhibits the NS5A protein, preventing the virus from spreading further. 

This dual-action mechanism disrupts the life cycle of Hepatitis C, leading to its eradication from the body. The combination therapy makes treatment more effective and shortens recovery time.

Velasof Tablet 400 mg/100 mg benefits include:

• Stops HCV replication, ensuring a sustained viral response
• Works against all major HCV genotypes
• Prevents liver damage and inflammation
• Shorter treatment duration compared to older therapies
• Safe for most patients with chronic Hepatitis C
• Well-tolerated with minimal side effects
• Helps restore liver health by eliminating the virus
• Convenient oral treatment requiring no injections
• Reduces the risk of long-term complications like liver cancer

The once-daily oral regimen ensures ease of use and better adherence to therapy this increases cure rate for Hepatitis C.

Dosage and how to take Velasof Tablet

Velasof should be taken as prescribed by your doctor. Some general guidelines for taking this medicine are: 

• Take 1 tablet at the same time every day.
• Swallow the tablet whole with water. Avoid chewing, crushing, or breaking it.
• Maintain a consistent schedule for optimal results. Avoid missing doses to ensure effective viral suppression. It is usually taken with food.
• Typically taken for 12 or 24 weeks as per the infection.

Side effects

Velasof Tablet is generally well-tolerated, but some users may experience:

• Fatigue
• Headache
• Nausea
• Insomnia
• Diarrhea
• Irritability

Most of these side effects are mild and subside as the body adjusts to the dose. However, if the above-mentioned symptoms cause serious discomfort, visit your doctor immediately.

Interactions

Before starting Velasof, it is important to understand how it interacts with other medications and food. Certain drugs and dietary choices can impact its effectiveness.

Drug interactions

Some medicines may interfere with the absorption or action of Velasof Tablet, reducing its effectiveness. 

Avoid taking Velasof Tablet with:

• Rifampin (reduces drug effectiveness)
• Carbamazepine (lowers Velasof levels)
• Phenytoin (decreases antiviral action)
• Amiodarone (risk of severe bradycardia)
• St. John's Wort (reduces therapeutic effects)

If you are on any of these medications, consult your doctor for alternative treatment options.

Disease interactions

Certain health conditions may require special precautions before using Velasof Tablet. Always discuss your medical history with your doctor.

• Liver disease: Consult a doctor before use if liver function is severely impaired.
• Kidney disease: Patients with severe renal impairment should be closely monitored.
• HIV co-infection: Dosage adjustments may be required when taken with antiretroviral therapy.

Patients with pre-existing conditions should follow a doctor’s advice to ensure safe use.

Food interactions

Diet can influence the absorption and effectiveness of Velasof Tablet. While the medication can be taken with or without food, certain dietary choices should be avoided.

• Grapefruit grapefruit juice: This may interfere with drug metabolism and reduce effectiveness.
• High-fat meals: This can delay absorption but does not significantly affect the overall action.
• Alcohol: This should be avoided as it can increase liver toxicity and worsen Hepatitis C complications.

Precautions

Keep in mind the following when taking this tablet:

• Velasof is not recommended for individuals under 18 years of age.
• Consult a doctor before use if you are pregnant, planning to become pregnant, or breastfeeding.
• Do not use Velasof if you have a known allergy to any of its ingredients.
• If you have a history of liver or kidney problems, seek medical advice before using Velasof.
• Be cautious when taking Velasof if you have a history of heart conditions or Hypertension.
• If you experience severe dizziness, headache, or blurry vision, stop using Velasof and consult your doctor immediately.

Why buy from us

When you purchase Velasof Tablet from GoodRxMedicine, you enjoy:

• Exclusive discounts and affordable prices
• Positive reviews from satisfied customers
• 24/7 customer support to help you with any inquiries
• Guaranteed availability of high-quality medicines with the same ingredients

FAQs

Is Velasof addictive?

No, Velasof is not considered an addictive or habit forming medicine, but it should be used only as prescribed by your doctor. Its misuse can lead to unwanted or severe side effects.

What should I do if I miss a dose of Velasof?

If you miss a dose of Velasof, take it as soon as you remember about the missed dose. If it is almost time for your next dose, skip this forgotten dose and continue your regular schedule. Do not take two doses at once.

Can Velasof affect my ability to drive?

Yes, Velasof may sometimes cause dizziness or drowsiness in some people. If you experience these side effects, avoid activities such as driving or using machinery until you feel better.

What should I do if I overdose on Velasof?

In case you suspect an overdose of Velasof, seek immediate medical attention or contact a poison control center immediately. A few symptoms of overdose may include dizziness, confusion, or fainting.

How does Velasof affect sleep?

Velasof may cause drowsiness in some individuals, helping with sleep in cases of anxiety or Depression. However, if you experience sleep disturbances or Insomnia issues, consult your doctor for advice.