Seroflo Inhaler 25 Mcg + 250 Mcg

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Dr. Akanksha Kaushal

Dr. Akanksha, Pharm-D

Dr. Akansha is a licensed Clinical Pharmacologist with extensive expertise in pharmacovigilance, prescription analysis, drug information, and safety. She's a dedicated educator and avid learner. Dr. Akansha also reviews medical content on GoodRxMedicine, ensuring accurate pharmaceutical information is accessible to all.

Written by

Julian Carter

Julian Carter

Julian, an MBA in Pharmaceutical Management, brings a dynamic blend of expertise and impact with his contributions at GoodRxMedicine. His dedication and innovative spirit continue to shape a brighter future in pharmaceutical management.

What is Seroflo Inhaler

Seroflo Inhaler​​ 25 mcg + 250 mcg is formulated to treat Chronic Obstructive Pulmonary Disease (COPD) and Asthma. It contains two active ingredients: Salmeterol, a Bronchodilator, and Fluticasone Propionate, a Corticosteroid. 

This combination helps alleviate symptoms such as wheezing, shortness of breath, and coughing. The Inhaler is typically used regularly to control respiratory conditions. 

Seroflo Inhaler​​ is widely manufactured and marketed by Cipla Ltd.

Uses of Seroflo Inhaler

Seroflo Inhaler​​ (25 mcg Salmeterol + 250 mcg Fluticasone Propionate) is primarily beneficial in managing respiratory conditions such as Asthma and COPD. 

• Asthma management: Seroflo helps improve Asthma symptoms, including chest tightness, wheezing, shortness of breath, and a chronic cough.
• COPD treatment: For individuals with COPD, Seroflo Inhalers improve lung function and minimize the severity of symptoms such as Chronic Bronchitis and Emphysema. 

Working and benefits of Salmeterol and Fluticasone Propionate

Salmeterol, a long-acting Bronchodilator, relaxes the airways' muscles, making breathing easier. Fluticasone Propionate, a corticosteroid, decreases inflammation by blocking certain chemicals that cause swelling in the airways. 

When used together, they provide better control of Asthma symptoms and improve lung function than either medication alone. This combination helps prevent wheezing, shortness of breath, and other respiratory issues, enhancing overall breathing comfort.

The combination of Fluticasone Propionate and Salmeterol offers several advantages:

• Synergistic effects: This dual action leads to better control of Asthma symptoms and a reduction in adverse effects compared to using each medication alone.
• Improved lung function: Clinical results have shown that combination therapy significantly improves lung function metrics. Improvement is seen in Forced Expiratory Volume (FEV1) compared to those using either drug individually.
• Reduction in adverse effects.
• Convenience: Administering both medications through a single Inhaler simplifies patient treatment regimens, improving therapy adherence.
• Cost-effectiveness: Combination therapy is more cost-effective than using either medication separately.

Dosage and how to take Seroflo Inhaler​​

Seroflo Inhaler​​ is prescription-based and should be taken as per a healthcare professional's instructions.

However, you can follow a few steps to increase the effectiveness of this medication:

• Dosage for Asthma and COPD in adults (18 years and older): Two inhalations (puffs) twice daily.
• Shake the Inhaler well before use. While taking a deep breath, press down on the inhaler to release the medication. Hold your breath for around 10 seconds to allow the drug to enter your lungs.
• Inhale the medication through the mouth only.
• If you miss your dose of Seroflo Inhaler, take the medication as soon as you remember, but skip the missing dose if your next dose is coming up.  
• In case of a Seroflo Inhaler overdose, seek urgent medical help to address potential side effects.

Side effects

Like any medication, Seroflo Inhaler​​ may cause some side effects. These adverse effects are temporary and will subside as your body adjusts.

However, consult a healthcare professional if the side effects persist or worsen. 

The side effects of using Seroflo Inhaler​​ are as follows: 

• Nausea and Vomiting
• Headache
• Cough
• Dry mouth
• Hoarseness of voice
• Sore throat

Interactions

Like most medications, Seroflo Inhaler​​ may interact with other medicines you take, your health conditions, or specific foods or drinks.

Drug interactions

The below-listed medicines listed might affect the effectiveness when taken along with Seroflo:

• Desmopressin: Co-administration is not recommended due to potential adverse effects.
• Levoketoconazole: If used together, it may lead to significant interactions.
• Beta-blockers: Acebutolol and Metoprolol may reduce Salmeterol's effectiveness, leading to Bronchospasm.
• Ketoconazole: Increases fluticasone levels, heightening the risk of side effects.
• Ritonavir: Used for HIV treatment, it may also elevate Fluticasone levels.

These exchanges highlight the importance of speaking with medical professionals when using Seroflo Inhaler alongside other medications.

Disease interactions

Seroflo Inhaler​​ has notable interactions with various medical conditions:

• Cardiovascular disorders: It may trigger Hypertension or Heart disease.
• Diabetes: Patients with Diabetes should use Seroflo cautiously as it may affect blood sugar levels.
• Thyroid disorders: Those with Hyperthyroidism may experience adverse symptoms due to Salmeterol.
• Fungal, bacterial, or viral infections: The Inhaler can raise the possibility of oral and throat fungus infections, especially in immunocompromised patients.
• Hypokalemia (low potassium levels): Seroflo can further lower potassium levels, leading to complications for patients already suffering from Hypokalemia.
• Osteoporosis: Long-term use of Corticosteroids like Fluticasone can increase the risk of bone density loss, making it a concern for patients with Osteoporosis.
• Glaucoma and Cataracts: Corticosteroids may increase Intraocular Pressure, worsening conditions like Glaucoma or Cataracts.
• Tuberculosis: Use in patients with active Tuberculosis is not recommended, as Corticosteroids can suppress the immune response

Patients should consult their healthcare provider regarding these interactions and any underlying health conditions before using the Seroflo Inhaler.

Food interactions

Food choices can impact the effectiveness of the Seroflo Inhaler​​ for the patient. Keep these points in mind:.

• Grapefruit juice: Consumption can increase Fluticasone levels in the body, potentially causing side effects.
• Caution with alcohol: The interaction of Seroflo with alcohol is not well documented, but it is recommended that you limit or avoid drinking when taking this inhaler.

These recommendations aim to optimize the effectiveness of the medication and minimize any potential severity of respiratory symptoms.

Precautions

Before starting the Seroflo Inhaler​​, it is essential to consider the following:

• Inhalation only: Use the Seroflo Inhaler strictly for inhalation, and do not swallow it.
• Rinse mouth: Rinse your mouth and throat with water or brush your teeth after each use to prevent fungal infections.
• First dose monitoring: Take the first dose under medical care due to the possibility of Bronchospasm.
• Pregnant or breastfeeding women: Always consult a doctor before using Seroflo during pregnancy or while breastfeeding to assess the benefits and risks involved.
• Avoid triggers: Try to avoid known Asthma triggers and do not smoke, as it can worsen symptoms.
• Children's use: Not recommended for children under 12 years without medical advice.
• Avoid stopping medication abruptly: Don't discontinue use without consulting your doctor, as this may trigger Asthma symptoms.
• During Asthma attacks: It is not used for immediate relief during an Asthma attack.

Following these precautions assures the patients of the benefits and minimal negative impacts of the Seroflo Inhaler​​ under medical supervision.

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FAQs

How long does Seroflo take to work?

Seroflo typically starts to work within 20 to 30 minutes after inhalation. However, maximum effectiveness may take a few weeks of regular use. For optimal results, it's essential to use it consistently as prescribed.

Does Seroflo contain steroids?

Yes, Seroflo contains steroids. Its active ingredient, Fluticasone Propionate, is a Corticosteroid that helps reduce inflammation in the airways. It is combined with Salmeterol, a Bronchodilator, to treat respiratory conditions like Asthma and COPD.

Does Seroflo increase heart rate?

Yes, some individuals may experience an increased heart rate as a side effect of using Seroflo. This can occur alongside other symptoms like headaches and throat irritation. If such effects arise, monitoring by a healthcare provider is recommended.

Can we use Seroflo daily?

Yes, Seroflo can be used daily if prescribed by doctors, particularly for managing Asthma and COPD. Regular use helps control symptoms but should not be used for sudden breathing difficulties.

Are there any dietary restrictions while using Seroflo Inhaler 25 mcg + 250 mcg?

Yes, while using the Seroflo Inhaler 25 mcg + 250 mcg, it is advisable to avoid certain foods that may worsen Asthma symptoms. These include cabbage, beans, garlic, onions, shrimp, pickled foods, dried fruits, fried foods, carbonated drinks, and wine.