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What is Selgin tablet?
Selgin tablet is a medication containing Selegiline, a Monoamine Oxidase B inhibitor (MAO-B inhibitor) used in the treatment of Parkinson's disease. It belongs to a class of drugs that work by increasing Dopamine levels in the brain.
Manufactured by Intas Pharmaceuticals, this medication helps improve motor function and reduces the symptoms of Parkinson's disease, such as stiffness or shaking.
Uses of Selgin tablet
Selgin 5 mg tablets are primarily prescribed for Parkinson's disease treatment, especially in combination with levodopa therapy. It is best suited for Early-stage Parkinson's disease treatment. However, it effectively manages motor fluctuations in advanced Parkinson's disease.
These tablets are beneficial in improving daily activities and quality of life in Parkinson's patients. It also supports cognitive function in neurodegenerative conditions.
Working and benefits of Selegiline
Selegiline works by selectively inhibiting Monoamine Oxidase B (MAO-B), an enzyme that breaks down Dopamine in the brain. This mechanism helps preserve Dopamine levels, which are typically depleted by Parkinson's disease.
Key benefits include:
- Enhanced Dopamine availability: Selegiline is a Dopamine enhancer that prolongs the effects of naturally produced Dopamine.
- Improved motor function: Helps reduce tremors and muscle stiffness.
- Levodopa optimization: Makes levodopa therapy more effective.
- Neuroprotective effects: May help slow disease progression.
- Better daily functioning: Improves ability to perform routine activities.
- Reduced "off" periods: Helps maintain consistent symptom control.
The medication is particularly effective because it specifically targets the MAO-B enzyme, providing focused, therapeutic benefits while minimizing side effects.
Dosage and how to take Selgin tablet
Take Selgin 5 as prescribed by your healthcare provider. The general guidelines are as follows:
- It is typically taken twice daily, in the morning and early afternoon. To avoid sleep disturbances, take the last dose before 2 p.m.
- Swallow whole with water. Do not crush, chew, or break the tablet.
- It can be taken with or without food.
- Follow your doctor's instructions for maximum dosage.
Regular monitoring by a doctor is essential.
Side effects
While generally well-tolerated, some users may experience Selgin tablet side effects:
- Dizziness
- Insomnia
- Nausea
- Headache
- Dry mouth
- Mild anxiety
Most side effects are mild and temporary. Consult a healthcare professional in case of persistent or severe reactions.
Interactions
Like other medicines, Selgin 5 mg tablet may interact with certain foods, medicines, and diseases.
Drug Interactions
Selgin may interact with:
- Other MAO inhibitors
- Antidepressants (especially SSRIs)
- Meperidine
- Tramadol
- Certain cough/cold medications
Disease Interactions
Exercise caution if you have:
- Heart conditions: People with existing cardiac conditions may experience worsening symptoms or complications.
- Kidney disease: In individuals with severe renal dysfunction, the clearance of Selegiline may be affected, increasing the risk of toxicity.
- Liver impairment: The medicine can elevate liver enzymes, leading to potential liver toxicity.
- Sleep disorders: Selegiline can affect sleep patterns and may worsen existing sleep disorders, leading to increased daytime sleepiness or insomnia.
Food Interactions
- Tyramine: Avoid foods high in tyramine, like aged cheeses, cured meats, and fermented foods. These may cause dangerously high blood pressure.
- Caffeine intake: Caffeine can worsen side effects such as anxiety and insomnia when taken with Selegiline.
- Alcohol consumption: Avoid alcohol as it may increase drowsiness and could interact unpredictably with Selegiline.
Precautions
Take these precautions while using Selgin:
- Regular monitoring of blood pressure is necessary.
- Avoid abrupt discontinuation of the medication.
- Inform the healthcare provider about any mental health changes.
- Use caution when driving or operating machinery.
- Report any new or worsening symptoms immediately.
- Follow dietary restrictions as advised by your doctor.
- It is unsafe for pregnant and breastfeeding women.
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FAQs
Are there any contraindications for using Selgin tablet 5 mg?
Yes, Selgin is contraindicated in people taking certain Antidepressants, those with severe cardiovascular disease, and patients with known hypersensitivity to Selegiline. Always inform your doctor about your medical history and current medications.
How long does it take for Selgin tablet 5 mg to show effects?
Initial improvements are noticed within a few weeks of starting Selgin, though full therapeutic benefits may take 6-8 weeks to develop. Regular monitoring by your doctor will help assess the medication's effectiveness.
Can Selgin be taken alone, or must it be combined with other medications?
Selgin can be prescribed alone in early Parkinson's disease, but it's often most effective when combined with levodopa therapy. A doctor will determine the best treatment approach based on your condition.
What dietary restrictions should I follow while taking Selgin?
Avoid foods high in tyramine, including aged cheeses, cured meats, and fermented products. Your healthcare provider will provide a complete list of foods to avoid or limit while taking this medication.
Is it safe to stop taking Selgin suddenly?
No, do not stop taking Selgin abruptly without consulting a doctor. Sudden discontinuation may worsen Parkinson's symptoms. A doctor will create a plan to gradually reduce the dose if needed.