Rejun 50 Tablet

Medically Reviewed by

Dr. Akanksha Kaushal

Dr. Akanksha, Pharm-D

Dr. Akansha is a licensed Clinical Pharmacologist with extensive expertise in pharmacovigilance, prescription analysis, drug information, and safety. She's a dedicated educator and avid learner. Dr. Akansha also reviews medical content on GoodRxMedicine, ensuring accurate pharmaceutical information is accessible to all.

Written by

Julian Carter

Julian Carter

Julian, an MBA in Pharmaceutical Management, brings a dynamic blend of expertise and impact with his contributions at GoodRxMedicine. His dedication and innovative spirit continue to shape a brighter future in pharmaceutical management.

What is Rejun 50 mg tablet

Rejun 50 mg tablet is primarily used to treat female infertility. This medication is used to induce the process of ovulation (to release an egg from the ovary) in women. It is used in those women who are having difficulties conceiving due to ovulatory disorders, such as Polycystic Ovary Syndrome (PCOS). 

It contains Clomifene Citrate, also called Clomiphene, which belongs to an ovulation stimulant drug class. It stimulates the hormone production necessary for ovulation, enhancing pregnancy chances.

It is manufactured by Sanzyme Ltd. 

Uses of Rejun 50 tablet

Rejun 50 is primarily used to stimulate ovulation in women to increase their chances of becoming pregnant. It is used in: 

• Treating infertility: Primarily prescribed to help women conceive by inducing the ovulation process. 
• PCOS: Helps to cause ovulation in PCOS women, a condition that prevents naturally occurring ovulation.
• Manages menstrual abnormalities: This medication can help regulate the menstrual cycle in women.  
• Off-label use to treat male infertility: Used to improve sperm quality and hormone levels in men potentially.

Working and benefits of Clomifene

Clomifene present in the Rejun 50 mg medicine primarily helps to treat infertility in women who want to conceive but suffer from irregular or absent ovulation. 

This active salt is classified as a selective estrogen receptor modulator (SERM), which helps stimulate ovulation. It binds to estrogen receptors in various tissues, specifically in the hypothalamus and pituitary gland.

 Clomiphene prevents estrogen from attaching to specific receptors. Under normal circumstances, high estrogen levels signal the brain to inhibit the release of fertility hormones. 

These hormones include Gonadotropin-releasing hormone (GnRH), Follicle-stimulating hormone (FSH), and Luteinizing hormone (LH). By taking estrogen’s place, it stops the signal, allowing the brain to release GnRH, which induces ovulation. 

The increase in GnRH levels results in a subsequent release of FSH and LH, which stimulate the ovaries to develop and release eggs, elevating the chances of pregnancy. 

Here are the key benefits of Clomifene 50 mg tablet: 

• Induces ovulation: Stimulates the release of eggs from the ovaries in women with irregular or absent menstrual cycles.
• Improves pregnancy rates: In women with conditions like PCOS or unexplained infertility, Clomifene significantly increases the chances of pregnancy.
• Enhances follicular development:  It enhances FSH production to promote the development of multiple follicles. This increases the potential number of eggs available for fertilization.

Dosage and how to take Rejun 50 

Follow these general guidelines to use this ovulatory stimulant medication: 

• Take it as directed for the exact number of days at regular intervals prescribed. Rejun is usually prescribed for 5 days, starting on the 5th day of your menstrual period.
• Swallow the Rejun tablet as a whole. Do not crush, chew, or break it. 
• Take 1 tablet with or without food. 
• Do not exceed more than the recommended dosage unless prescribed by your doctor. 

Side effects

Clomifene is mostly tolerated well among individuals. However, in some instances, it can cause relatively few side effects, including: 

• Nausea
• Bloating
• Headache
• Breast pain
• Spotting
• Flushing

These side effects usually go away as your body adjusts to the dosage. Inform your doctor immediately if Rejun 50 side effects persist or worsen. 

Interactions

Clomifene may interact with other medicines, underlying health conditions, and foods you take. It is essential to understand the same to ensure optimum results. It is important to note that this list may not describe all possible interactions. Hence, consult your doctor for personalized advice. 

Drug interactions

Clomifene may interact with certain medications, which can affect its efficacy or increase potential side effects. These include: 

• Anticoagulants (e.g., Warfarin): It requires careful monitoring as Clomifene can alter its anticoagulant effects.
• Hormone Replacement Therapy (HRT): It can interfere with the medicine’s ability to induce ovulation.
• Gonadotropins (FSH, hCG): They may enhance ovarian stimulation, leading to an increase in the risk of Ovarian Hyperstimulation Syndrome (OHSS).
• Cyclosporine: Taking it together increases the risk of liver toxicity.
• Ospemifene: This may alter the hormonal balance and reduce the medicine’s effectiveness.
• Hormonal Contraceptives (like birth control pills): Clomifene can reduce their effectiveness to increase the chances of unintended pregnancy.

Disease interactions

Clomifene should be used with caution in individuals with the following conditions:

• Large ovary or ovarian cyst
• Endometriosis (a condition in which tissues similar to the uterus lining grow outside the uterus)
• Liver diseases
• Unusual uterine bleeding
• Uncontrolled thyroid or adrenal disorders
• Hormone-sensitive tumors

Food interactions

Certain foods or drinks can affect the efficacy of this medication. This includes: 

• Alcohol: It can increase the risk of potential side effects associated with Clomifene, such as dizziness and visual disturbances. It may also significantly affect liver function since Clomifene is metabolized.
• Caffeine: Excessive intake may elevate the risk of side effects like headaches or nervousness.

Precautions

Take note of these things before using this Rejun medication: 

• Do not use Rejun if you are pregnant or breastfeeding.  
• Avoid taking it if you have liver conditions. 
• Avoid if you are allergic to Clomifene or any of the medicine’s components. 
• Avoid using it if you have ovarian cysts (except those from PCOS), uterine fibroids, abnormal vaginal bleeding, a pituitary tumor, or thyroid or adrenal disease.

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FAQs

How long does it take to get pregnant after taking Rejun-50 tablet?

In clinical trials, about 50% of patients can conceive after roughly 3 cycles, aligning with the general population's success rates. However, individual results vary. Women may conceive within 3 to 6 cycles of treatment. Timing intercourse around ovulation is also essential; hence, consult your doctor for personalized advice. 

Does the Rejun-50 tablet help regularise periods?

Yes, Rejun-50 may help in regularising periods in women with irregular cycles due to a lack of ovulation. Since it stimulates the mechanism, this can indirectly lead to more regular menstrual cycles. However, consult your doctor for personalized guidance.

For how many cycles can I take the Rejun-50 tablet?

It is generally recommended that women take the Rejun-50 tablet for 3 menstrual cycles, which can increase to 4 under specific circumstances. While many women may conceive within this timeframe, it is better to consult their gynecologist for personalized guidance. 

After how many days of Rejun-50 tablet intake should I have sex to get pregnant?

It is suggested to plan intercourse approximately 5-10 days of post-Rejun 50 tablet treatment to maximize the chances of conception. However, your doctor may suggest the best days for intercourse based on ovulation timing. 

Can I take Rejun 50 tablet with Metformin?

Yes, you can take Rejun 50 with Metformin under medical supervision. This combination may be beneficial for women with conditions like PCOS, where both medications can help regulate ovulation. Always follow your healthcare provider's advice.