Penegra 50 Mg

Medically Reviewed by

Dr. Akanksha Kaushal

Dr. Akanksha, Pharm-D

Dr. Akansha is a licensed Clinical Pharmacologist with extensive expertise in pharmacovigilance, prescription analysis, drug information, and safety. She's a dedicated educator and avid learner. Dr. Akansha also reviews medical content on GoodRxMedicine, ensuring accurate pharmaceutical information is accessible to all.

Written by

Julian Carter

Julian Carter

Julian, an MBA in Pharmaceutical Management, brings a dynamic blend of expertise and impact with his contributions at GoodRxMedicine. His dedication and innovative spirit continue to shape a brighter future in pharmaceutical management.

What is Penegra 50

Penegra 50 mg is a prescription medication used to treat Erectile Dysfunction (ED) in males. It includes Sildenafil, a Phosphodiesterase type 5 (PDE5) inhibitor that boosts blood supply to the penis during sexual stimulation, assisting in the development and maintenance of an erection. 

Penegra 50 mg tablet typically begins its action within 30-60 minutes and lasts about 4-6 hours. However, sexual stimulation is required for the medicine to show its effect. 

A renowned pharma firm, Zydus Cadila, primarily manufactures the medication.

Uses of Penegra 50

Penegra 50 is an oral ED therapy that enhances your sexual performance by:

• Managing ED by boosting blood supply to the penis, leading to an erection.
• Improves sexual performance by resolving issues in getting or maintaining an erection.
• It improves quality of life by reducing the psychological distress caused by ED.
• In some cases, it can also be used to treat Pulmonary Arterial Hypertension (PAH), decreasing blood pressure in the lungs and increasing exercise capacity.

Working and benefits of Sildenafil

Sildenafil is a PDE5 enzyme primarily used to treat Erectile Dysfunction in men. It inhibits the PDE5 enzyme that disintegrates cyclic Guanosine Monophosphate (cGMP), a substance that dilates blood vessels. 

By inhibiting the PDE5 enzyme, Sildenafil raises cGMP levels in the penis. This, in turn, enhances the blood supply to the penis and enables an erection when you are sexually aroused.

Here are some key benefits of Sildenafil, making it an effective treatment for improving your sexual health:

• Erectile Dysfunction treatment: Sildenafil is well-known for its ability to assist roughly 80% of men in obtaining and sustaining an erection, which significantly enhances sexual performance.
• Rapid onset of action: The medicine normally works within 30 to 60 minutes after administration, making it appropriate for spontaneous sexual activity.
• Improved quality of life: By treating ED, Sildenafil improves overall sexual pleasure and intimacy, which benefits emotional well-being and relationships.
• Dual benefits: In some cases, Sildenafil helps treat PAH. It Reduces blood pressure in the lungs, increasing exercise capacity.
• Widely studied and trusted: Sildenafil has undergone thorough scientific studies to establish its safety and efficacy, making it a trustworthy alternative for treating ED.

Dosage and how to take Penegra 50

Take Penegra 50 mg pills after consulting your doctor. Here are some general usage guidelines:

• Have the medication 30-60 minutes before the planned sexual act.
• Take the pill with a full glass of water and consume it whole without breaking, crushing, or chewing it.
• The medicine can be taken with or without food; however, a high-fat meal may delay its onset of effect.
• Avoid taking more than one pill in a 24-hour period.

Side effects

Most side effects experienced by Penegra users are minor and subside as your body adjusts to the medicine. However, if they continue or raise concerns, consult your doctor.

Common side effects of Sildenafil are:

• Vomiting
• Dizziness
• Nausea
• Indigestion
• Nasal congestion

Interactions

Like any other medicine, Penegra 50 can interact with other prescription or over-the-counter medications, pre-existing health problems, and certain foods, increasing the chance of adverse effects.

Drug interactions

Penegra may interact with other medications, potentially reducing their efficacy or raising the likelihood of adverse effects. Some significant interactions include:

• Nitrates
• Alpha-blockers, such as Tamsulosin, Doxazosin
• Antihypertensives, including Amlodipine, Metoprolol
• Other ED pills like Vardenafil 

This is not the complete list. Consult your doctor regarding all the possible drug interactions before taking the medicine.

Disease interactions

Penegra 50 tablets can interact with some health conditions that should be addressed, including:

• Cardiovascular disease: Individuals with heart issues should exercise caution while taking the pill.
• Liver disease: Individuals with liver impairment may require dose changes due to changed medication metabolism.
• Kidney disease: Kidney failure can impair Sildenafil elimination from the body, necessitating close monitoring and potential dosage modifications.
• Seizure disorders: People with a history of seizures should be carefully watched while using this medicine.
• Bleeding disorders: Patients with bleeding problems should exercise caution since Sildenafil may increase the risk of bleeding.

Food interactions 

Here are some common food interactions of Penegra that should be considered while having the pill:

• Grapefruit: Avoid consuming grapefruit or drinking grapefruit juice while taking Penegra. This might raise Sildenafil levels in the body, potentially leading to increased side effects.
• High-fat meals: Although Penegra can be taken with or without food, high-fat meals may slow absorption and efficiency.
• Alcohol: Restrict your alcohol intake as it can raise the risk of adverse effects, including dizziness and headache.

Precautions

Take the following precautions while having the medicine to minimize the risk of any side effects:

• Inform your doctor about your medical history, including heart, liver, or kidney concerns.
• Do not use Penegra if you are allergic to Sildenafil or any of its components.
• Get medical assistance immediately if you encounter unexpected vision loss or eye-light changes.
• If you suffer dizziness or impaired vision after taking this medication, be careful when driving or using machinery.
• Penegra is not suggested for usage by women or anybody under the age of 18.
• Before using this product, discuss any penile deformities or disorders, such as Peyronie's disease, with your doctor.

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FAQs

Does Penegra raise testosterone levels?

No, Penegra does not directly raise testosterone levels. It works by boosting blood supply to the penis, although some studies show it may have little impact on hormone balance over time.

Can I take Penegra every day?

No. Penegra is typically taken as needed, around 30-60 minutes before sexual activity. Taking it daily may enhance the chances of side effects. Consult your doctor before considering the pill for daily use.

Is Penegra safe for people with Diabetes?

Yes. Many people with Diabetes can safely take Penegra for ED. However, it is essential to consult a doctor before taking the pill since Diabetes-related issues may necessitate dose modifications.

What can I do if Penegra does not work for me?

If the Penegra tablet does not work, talk to your doctor. Factors like dosage, underlying health conditions, or psychological factors may play a role, and alternative treatments may be available.

Does Penegra affect sperm count or fertility?

No. Penegra has no adverse effect on sperm count or fertility. Some studies indicate that it may even increase sperm motility by increasing blood supply to the reproductive organs. However, the long-term consequences on fertility are unknown, and a doctor is suggested for individualized counsel.