Oestrogel 2.5 gm/1.5 mg

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Dr. Akanksha Kaushal

Dr. Akanksha, Pharm-D

Dr. Akansha is a licensed Clinical Pharmacologist with extensive expertise in pharmacovigilance, prescription analysis, drug information, and safety. She's a dedicated educator and avid learner. Dr. Akansha also reviews medical content on GoodRxMedicine, ensuring accurate pharmaceutical information is accessible to all.

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Julian Carter

Julian Carter

Julian, an MBA in Pharmaceutical Management, brings a dynamic blend of expertise and impact with his contributions at GoodRxMedicine. His dedication and innovative spirit continue to shape a brighter future in pharmaceutical management.

What is Oestrogel

Oestrogel is a prescription Hormone Replacement Therapy (HRT) that primarily treats menopausal symptoms, such as hot flashes, vaginal dryness, and itching in women.  It contains Estradiol, an FDA-approved active ingredient, and belongs to the Estrogen class of medicines. 

It works by replacing the Estrogen hormone and increasing its level in the women’s body. Therefore, this transdermal gel effectively treats Estrogen deficiency and Osteoporosis (bone thinning) in women.

Besins Healthcare manufactures Osterogel which can effectively alleviate symptoms associated with Menopause.

Uses of Oestrogel

Oestrogel is a topical HRT primarily used in postmenopausal women. Some significant Oestrogel uses are as follows:

• Relieves menopausal symptoms: Being an HRT, this gel is primarily employed to relieve menopausal symptoms in women. It is used for the alleviation of vaginal dryness, itching, night sweats, and hot flashes. Furthermore, it can also increase libido in women.
• Prevents Osteoporosis: It is indicated for preventing Osteoporosis in postmenopausal women, helping to maintain bone density and reduce fracture risk.
• Prostate Cancer: In some cases, your doctor can prescribe this topical Estrogen treatment to relieve Prostate Cancer in men.

Working and benefits of Estradiol

Estradiol works by replacing Estrogen, primarily produced by ovaries. As a result, it manages the Estrogen levels in the body so that you can have a pre-menstrual hormonal level. When you apply the gel on the skin, the hormone is absorbed into your bloodstream, relieving menopausal symptoms.

Taking the medicine in the prescribed doses gives you various benefits. Here are the key benefits of Oestrogel for women:

• FDA-approved Estradiol: The topical gel contains FDA-approved Estradiol.
• Rapid Absorption: It is quickly absorbed through the skin, allowing for a steady release of Estrogen into the bloodstream. It can help maintain consistent hormone levels throughout the day.
• Faster visible results: When used in prescribed doses, your symptoms can improve within 3 months.
• Convenient application: The gel form allows easy application without the need for daily pills, making it a user-friendly option for many women.
• Improved vaginal health: The Estradiol gel can enhance vaginal moisture, reducing dryness and irritation, which can improve women’s health and comfort during intercourse.

Dosage and how to apply Oestrogel

It is a topical Estrogen treatment used for external purposes only. Generally, when you consult a doctor, they prescribe the best dosage and ideal time to use this medication. Therefore, adhering to the prescribed dosage and duration is necessary for safe use and effective results

For the most Oestrogel benefits, follow the given guidelines:

• Use the gel only in the prescribed dosage.
• Wash and dry the area. Collect the prescribed pumps (dose) of the gel and apply it gently to either the outer arms and shoulder of both hands or the mid-inner thighs of both legs. Do not rub or massage the gel, and let it dry. Wash your hands after applying the gel.
• Do not apply the gel on your face, genital area, or breast. Also, do not wash the application site for at least an hour.
• Use this medication once or as directed by your doctor daily at the same time.

Side effects

Oestrogel may sometimes cause side effects that are normal for the first few uses in some women. These are generally mild and may subside as the body adapts to the medicine or its adjusted dosage.

The side effects usually do not need immediate medical attention. However, if they persist for longer or worsen, consult your doctor and seek treatment.

Some common Oestrogel side effects are as follows:

• Itching or skin rash
• Hair loss
• Breast pain or enlargement
• Joint pain
• Headache
• Uterine bleeding

Interactions

Like all medications, Oetrogel may also interact with other medicines you take, your pre-existing medical condition, or dietary choices.

Drug interactions

Being an HRT, there are certain chances this medicine may interact with the medications you take. Inform your doctor if you take any of the following medications before using this topical gel:

• Amoxicillin
• Cyclosporin
• Ampicillin
• Cefixime
• Penicillin G
• Warfarin

This is not an inclusive list. Please consult your doctor and discuss any possible interactions with any medicine you take.

Disease interactions

Oestrogel may interact with your ongoing medical conditions, leading to severe consequences. It is recommended to inform your doctor about your medical history and use this medicine with caution:

• Hypertension: People with high blood pressure should not use this medicine without consulting their doctor.
• Kidney disease: You should consult your doctor if you have/had kidney impairment before using this medicine.
• Liver disease: It should not be used by women with liver diseases, as it can interact with liver function or worsen the ongoing liver disease.
• Heart problems: Consult your doctor if you have a heart disease before using this medicine.
• Bleeding or blood clot disorder: You should not use this medicine if you have a bleeding or blood clot.

Food interactions

Before using Oestrogel 2.5gm/1.5 mg, inform your doctor about your dietary choices and supplements to reduce the risk of interactions.

• Grapefruit and its juices: Grapefruit can change the amount of Estrogen absorbed by the body, leading to unwanted side effects.
• St John’s Wort: It can increase the breakdown of Estradiol and affect its effectiveness.

Precautions

Like all HRTs, Estradiol gel should be taken with extreme caution. Follow the given precautions before using this topical gel:

• Do not use this gel if allergic to its active ingredient or other component.
• The topical medicine is intended for postmenopausal or women approaching Menopause. Do not use it if you are below 18 years old.
• Avoid excessive alcohol or smoking while on your HRT.
• The medicine may increase the risks of Breast Cancer. Be sure to get regular breast examinations to reduce the risks of developing cancer.
• Estradiol is highly unsafe for pregnant and breastfeeding women. Always inform your doctor if you are pregnant, planning pregnancy, or breastfeeding before using this medicine.
• If you still have an intact womb (women who have a womb and haven’t menstruated for more than six months), consult your doctor before taking this HRT. In this case, your doctor will more likely prescribe other HRT that contain Progesterone.

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FAQs

What is the best place to apply Oestrogel?

The best place to apply this medicine is either your outer arms and shoulder of both hands or the mid-inner thighs of both your legs. Do not apply the gel on your face, breast, or genital area. The medicine is intended for external use only and should not be applied in vagina or mouth.

Can I apply Oestrogel at night?

Yes, you can apply it at night if your doctor prescribes it. However, it is necessary to use the medicine at the same time every day and maintain an optimal gap between the two doses. You can consult your doctor to prescribe the best time to use this medicine.

How long does Oestrogel 2.5 gm/1.5 mg take to show effects?

It typically begins to show effects within a few weeks of regular use. However, you may observe its full benefits within three months of consistent use. Using the medicine in the prescribed dosage and duration is essential for optimal results. Also, visit your doctor regularly to examine your improvements or dosage adjustments. 

Can Oestrogel 2.5 gm/1.5 mg be combined with other hormone therapies?

Yes, you can use Oestrogel with other hormone therapies that contain Progesterone if your doctor prescribes it. It usually happens when you still have an intact womb (women who have a womb and haven’t menstruated for more than six months). However, it is necessary to consult your doctor before combining it with any medicine.

Are there any storage instructions for Oestrogel 2.5 gm/1.5 mg?

Yes, you should store this medicine below 25℃. Keep this medicine away from direct sunlight and moisture. Keep this topical gel away from the reach of children and pets. Furthermore, if you have used the entire product, you should dispose of it safely.