Neukine 300 Mcg Injection

Medically Reviewed by

Dr. Akanksha Kaushal

Dr. Akanksha, Pharm-D

Dr. Akansha is a licensed Clinical Pharmacologist with extensive expertise in pharmacovigilance, prescription analysis, drug information, and safety. She's a dedicated educator and avid learner. Dr. Akansha also reviews medical content on GoodRxMedicine, ensuring accurate pharmaceutical information is accessible to all.

Written by

Julian Carter

Julian Carter

Julian, an MBA in Pharmaceutical Management, brings a dynamic blend of expertise and impact with his contributions at GoodRxMedicine. His dedication and innovative spirit continue to shape a brighter future in pharmaceutical management.

What is Neukine 300 mcg Injection

Neukine 300 mcg Injection is an effective treatment for preventing infections in patients after chemotherapy and bone marrow transplant. 

It contains Filgrastim, which is in the class of medications called Granulocyte colony-stimulating factor (G-CSF). It enhances the immune response by stimulating the production and activation of neutrophils, a type of white blood cell essential for fighting infections.

It is manufactured by Intas Pharmaceuticals Ltd., a leading pharmaceutical company in the world. 

Uses of Neukine 300 mcg Injection

Neukine 300 mcg Injection, containing Filgrastim, helps stimulate the production of white blood cells. It helps to: 

• It primarily helps in neutropenia treatment in which the body has a low concentration of neutrophils in the blood. This injection increases patients' white blood cell count after chemotherapy or bone marrow transplantation. 
• It also treats conditions such as chronic neutropenia and neutropenia in HIV-infected individuals. 
• Enhances recovery before stem cell donation. 
• Reduces fever duration in patients with acute Myeloid Leukemia and supports recovery from radiation exposure.

Working and benefits of Filgrastim

Neukine 300 mcg Injection contains Filgrastim, which helps to increase the number of immune cells in the body. It binds to specific G-CSF receptors on hematopoietic progenitor cells (stem cells that give rise to other blood cells) in the bone marrow. 

When this binding happens, it activates signals inside the cells to multiply, develop into neutrophils, and mature to fight infections. This medicine helps develop neutrophils from the bone marrow into the bloodstream. The quantity of these immune cells significantly increases, enhancing the body’s ability to combat infections. 

This active salt also boosts neutrophils’ function by improving their reaction time and ability to fight infections-causing microorganisms. 

Key benefits of this injection include: 

• Boosts white blood cell production: Increasing the amount of neutrophils in the body. 

• Reduces the risk of infections: Neutrophils boost combat infections. 

• Improves immune function: Enhances neutrophils activity, making them effective against bacteria and viruses. 
• Supports bone marrow transplant patients: Aids in restoring the levels of blood cells after bone marrow transplantation. 

This provides a reliable solution for patients requiring increased white blood cells to help treat infections. 

Dosage and how to take Neukine 300 mcg Injection

Follow these instructions to take the injection safely and effectively:

• Take the injection at least 24 hours after the chemotherapy session or bone marrow transplant.
• Take this injection only from a trained healthcare professional. It is given subcutaneously (under the skin) or intravenously (into a vein). Do not self-administer unless an expert trains you. 
• Filgrastim injections can be taken with or without food. Consult your doctor for personalized advice. 
• It is typically given daily until your white blood cell normalizes. 

Consult the doctor for personalized guidance to ensure safe and effective Neukine usage.

Neukine 300 mcg side effects

Though Neukine is generally well-tolerated, in some instances, users may experience side effects, including:  

• Headache
• Weakness
• Bone pain
• Rash
• Nausea

These side effects are usually temporary and mild. However, if they continue or worsen, seek medical assistance immediately.

Interactions

Like most medications, Neukine may interact with certain medications, health conditions, and specific foods or drinks. 

Drug interactions

Neukine may interact with various medications, which may affect its efficacy. These include: 

• Methotrexate
• Azathioprine
• Bendamustine
• Busulfan
• Hematopoietic Agents

This is not a comprehensive list. Kindly consult with your healthcare provider for personalized guidance. 

Disease interactions

Neukine requires caution in the following conditions: 

• Leukocytosis: Lead to potential complications.
• Sickle Cell Anemia: Increase the risk of complications.
• Kidney Disease: Dosage adjustments might be necessary.
• Osteoporosis (Bone thinning): Close monitoring may be required. 
• Splenic Issues: Neukine can cause splenic enlargement or severe abdominal pain. 
• Heart Problems: Potential adverse impact on cardiovascular health. 

Food interactions

Neukine 300 mcg does not have any known significant food interactions. Consult your healthcare provider for personalized guidance. 

Precautions

Before using this injection, it is essential to take note of the following: 

• Inform your healthcare professional if you are pregnant, planning to conceive or breastfeeding. Due to the limited information available, caution is advised. 
• Do not use this injection if you are allergic to Filgrastim or its components. 
• Do not take the pill without consulting a doctor if you have conditions such as sickle cell anemia, osteoporosis, or heart problems. 
• Medical supervision is required if used for children. 
• Do not stop the treatment without informing your doctor to ensure proper recovery.

Why buy from us

When you buy Neukine online from GoodRxMedicine, you enjoy benefits such as:

• Exclusive discounts and competitive pricing
• Discreet packaging to prioritize your privacy 
• Dedicated customer support is available 24/7
• Same-day shipping and on-time delivery

Experience convenience and reliability when you choose us for your pharmaceutical needs.

FAQs

Are there any dietary restrictions while using Neukine 300 mcg Injection?

No strict dietary restrictions exist when using Neukine 300 mcg injection. However, maintaining a balanced diet in antioxidants like berries and spinach is recommended to support immune function. Avoid alcohol and excessive caffeine, and drink plenty of water. Consult your doctor for personalized advice. 

What should I do if I miss a dose of Neukine 300 mcg Injection?

If you miss a Neukine dose, inform your doctor or nurse immediately. They will guide you on the next steps. If your next dose isn’t close, it may be given immediately; otherwise, it might be skipped to maintain the regular schedule. Never take a double dose without medical advice.

When is the best time to inject Filgrastim?

Filgrastim is usually given once daily for seven days. The dosage typically starts on the fourth day of the chemotherapy cycle. However, the schedule may vary based on individual treatment plans.

Can Neukine cause allergic reactions?

Yes, in rare instances, Neukine injection can cause allergic reactions such as rash, swelling, breathing difficulties, or dizziness. Seek medical attention immediately if you notice any signs of an allergic reaction.

Does Neukine 300mcg Injection cause cancer?

No, Neukine injection does not cause cancer. It is a white blood cell booster in patients undergoing chemotherapy or with low neutrophil levels. While it helps prevent infections, it has not been linked to cancer. Hence, use it as your doctor advises.