Natamet 5% 3 ml

Medically Reviewed by

Dr. Akanksha Kaushal

Dr. Akanksha, Pharm-D

Dr. Akansha is a licensed Clinical Pharmacologist with extensive expertise in pharmacovigilance, prescription analysis, drug information, and safety. She's a dedicated educator and avid learner. Dr. Akansha also reviews medical content on GoodRxMedicine, ensuring accurate pharmaceutical information is accessible to all.

Written by

Julian Carter

Julian Carter

Julian, an MBA in Pharmaceutical Management, brings a dynamic blend of expertise and impact with his contributions at GoodRxMedicine. His dedication and innovative spirit continue to shape a brighter future in pharmaceutical management.

What is Natamet?

Natamet eye drops contain Natamycin, a polyene antifungal medication specifically designed to treat fungal eye infections. It belongs to the macrolide antifungal class and effectively targets various fungal species affecting the eye. 

Sun Pharmaceutical Industries Ltd manufactures this prescription medication to meet the highest quality standards for ophthalmic use.

Uses of Natamet

These eye drops are primarily prescribed for fungal infections. The active ingredient, Natamycin, stops fungal growth and treats infections. 

Its uses are as follows:

• Treatment of fungal keratitis (corneal infections)
• Management of fungal conjunctivitis
• Prevention of fungal infections in high-risk patients
• Treatment of superficial ocular fungal infections
• Post-surgical fungal infection prevention
• Treatment of Aspergillus and Fusarium infections

Working and benefits of Natamycin

Natamycin works by binding to Ergosterol in fungal cell membranes, causing cell death. This unique mechanism makes it highly effective against various fungal species while being safe for human tissue.

Key benefits include:

• Targeted antifungal action: Specifically attacks fungal cells and stops fungal growth. 
• Broad spectrum activity: Effective against various fungi. 
• Surface retention: Remains active on eye surface. 
• Minimal resistance: Fungi rarely develop resistance. 
• Safe for corneal use: Doesn't harm corneal tissue. 
• Quick action: Starts working within 24-48 hours. 

The medication is particularly effective because it penetrates fungal cells while having minimal effect on human cells. However, it is ineffective for bacterial eye infections. In such cases, medical advice is necessary. 

Dosage and how to use Natamet

It should be used as prescribed for best results. The general guidelines are as follows:

• Apply one drop every 1-2 hours initially, as directed. 
• Wash hands before and after application. Avoid touching the dropper tip. Keep eyes closed for 1-2 minutes after application. 
• Allow 5 minutes between different eye medications. 
• Continue treatment for at least 4-6 weeks or as prescribed. Do not exceed the recommended dosage. 

Side effects

While these eye drops are generally well-tolerated, some users may experience:

• Mild eye irritation
• Temporary burning sensation
• Eye pain
• Blurred vision
• Tearing
• Redness
• Foreign body sensation

Most side effects are temporary and mild. Consult your eye specialist if symptoms persist.

Interactions

Natamet eye drops may interact with other medicines and diseases as follows:

Drug Interactions

Use caution when combining with:

• Other eye medications
• Contact lenses
• Steroid eye drops
• Eye ointments
• Artificial tears

Disease Interactions

Exercise caution if you have:

• Severe eye inflammation:  Severe inflammation can complicate the healing process. Natamycin may not effectively lower inflammation. So, caution is necessary. 
• Contact lens-related complications: Natamycin is effective against fungal infections but does not treat bacterial infections that may also arise from contact lens use. Thus, careful management of contact lens hygiene and prompt treatment of any signs of infection are crucial. 
• History of eye surgery: Previous surgeries can alter the integrity of the corneal surface, making it more susceptible to infections. While Natamycin can treat fungal infections, consulting a doctor is essential. 
• Concurrent bacterial infections: Natamycin is ineffective against bacteria. If a person presents with a mixed infection (both bacterial and fungal), additional antibiotic therapy will be required to ensure comprehensive treatment.

Food Interactions

As Natamet is an ophthalmic solution, there are no direct food interactions. 

Precautions

Take these precautions while using Natamycin:

• Complete the full course of treatment. 
• Don't wear contact lenses during treatment. 
• Keep the bottle tightly closed. 
• Discard unused medication after 28 days. 
• Don't touch the tip of the eye dropper. 
• Regular follow-up with an eye specialist. 
• Avoid driving as it may cause temporary blurred vision.
• If pregnant or breastfeeding, inform the doctor. 

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FAQs

I am using another type of eye medicine, can I use Natamet Eye Drops?

Inform your doctor about all eye medications you're using before these eye drops to avoid interactions. Always maintain a 5-minute gap between different eye medications to prevent the risk of adverse effects. 

What are the foods to avoid while using Natamet Eye Drops?

There are no specific food restrictions while using Natamycin Eye Drops as it is an ophthalmic solution. However, maintain good hygiene and follow a healthy diet to support overall eye health.

Is Natamet Eye Drops used for other eye infections?

No, it is specifically designed to treat fungal eye infections. It works by stopping fungal growth. It is not effective against bacterial or viral eye infections. For other infections, consult an ophthalmologist for appropriate treatment. 

Does Natamet Eye Drops cause cancer?

No, there is no evidence linking these eye drops to cancer. It's a well-established antifungal medication with a long safety record. However, if you have concerns, discuss the risks and benefits of Natamet with your doctor. 

Why Natamet Eye Drops does not affect bacteria?

Natamycin works by targeting Ergosterol, a component found in fungal cell membranes but not in bacterial cells. This makes it specific to fungal infections only. So, it is ineffective against bacterial eye infections.