Malegra DXT Plus

Medically Reviewed by

Dr. Akanksha Kaushal

Dr. Akanksha, Pharm-D

Dr. Akansha is a licensed Clinical Pharmacologist with extensive expertise in pharmacovigilance, prescription analysis, drug information, and safety. She's a dedicated educator and avid learner. Dr. Akansha also reviews medical content on GoodRxMedicine, ensuring accurate pharmaceutical information is accessible to all.

Written by

Julian Carter

Julian Carter

Julian, an MBA in Pharmaceutical Management, brings a dynamic blend of expertise and impact with his contributions at GoodRxMedicine. His dedication and innovative spirit continue to shape a brighter future in pharmaceutical management.

What is Malegra DXT Plus?

Malegra DXT Plus is a combination medicine that comprises 100 mg of Sildenafil Citrate and 60 mg of Duloxetine. Its primary usage is to treat Erectile Dysfunction (ED) and Premature Ejaculation (PE) in males. Sildenafil is a Phosphodiesterase type 5 (PDE5) inhibitor that enhances blood supply to the penis, thereby facilitating firm and long-lasting erections. 

On the other hand, Duloxetine is a Selective Serotonin and Norepinephrine Reuptake Inhibitor (SSNRI) that delays ejaculation. Sunrise Remedies Pvt. Ltd. manufactures the medication.

Uses of Malegra DXT Plus

The primary uses of Malegra DXT Plus are:

• Encourage blood flow to the penis, allowing for firm and long-lasting erections during sexual activity.
• Improves ejaculatory control, resulting in longer-lasting intercourse.
• It is beneficialBeneficial for men who struggle to sustain an erection and have early ejaculation simultaneously.
• Malegra DXT Plus can improve erection quality and postpone ejaculation, resulting in a more pleasurable sexual encounter.

Working and benefits of Sildenafil and Duloxetine

Malegra DXT Plus has two active ingredients: Sildenafil and Duloxetine. It is a combination medication intended to treat Erectile Dysfunction and Premature Ejaculation in males.

Sildenafil, a PDE5 inhibitor, primarily treats ED by boosting blood flow to the penis. It inhibits the PDE5 enzyme, which breaks down cyclic Guanosine Monophosphate (cGMP), a substance responsible for the relaxation of the blood vessels. 

When cGMP levels rise, the blood vessels in the penis relax and expand, resulting in stronger and more prolonged erections during sexual stimulation. Sildenafil does not create spontaneous erections but rather improves the body's natural reaction to sexual excitement.

Duloxetine, on the other hand, is an SSNRI that is commonly used as an antidepressant and to treat PE. It enhances Serotonin levels in the brain, thereby delaying ejaculation and improving ejaculatory control. 

Duloxetine increases neurotransmitter activity, allowing men to stay longer during intercourse while lowering Anxiety and stress associated with PE.

The combination of Sildenafil and Duloxetine in a single tablet provides a dual-action option for men who struggle to achieve and sustain erections while also managing ejaculation. This boosts sexual confidence, intimacy, and satisfaction. 

However, it should only be used under medical supervision because both medicines might have adverse reactions and interact with other medications.

Dosage and how to use Malegra DXT Plus

To ensure safe and effective use of the medicine, take it as directed by your doctor. Common guidelines are:

• Take the pill 30-60 minutes before engaging in sexual activity for optimal benefits.
• Swallow the whole pill with a glass of water. Never chew or crush it.
• Can be taken with or without food; however, a heavy or fatty meal may prolong its effects.
• Do not take more than 1 pill a day.

Side effects

Malegra DXT Plus can lead to some mild side effects that often disappear once your body adjusts to the medication. These side effects are:

• Dizziness
• Nausea
• Headache
• Nasal congestion
• Flushing (feeling of warmth on face and neck)

If any of these side effects persist or start bothering you, contact your healthcare provider for assistance.

Interactions

The medicine can interact with other medications, diseases, and food products, which need to be taken care of to reduce the risk of adverse reactions.

Drug interactions

Malegra can interact with medicines, that can reduce its efficacy. Below are the primary drug interactions to be aware of:

• Nitrates
• Blood pressure medicines
• Alpha-blockers
• Other ED pills
• Antidepressants

This list does not include all potential medicine interactions. For detailed information and appropriate medical advice, consult with your healthcare practitioner.

Disease interactions

Before using this medication, ensure you are aware of any potential disease interactions. Here are some important interactions:

• Cardiovascular diseases: Sildenafil in the medicine may reduce blood pressure. It is risky if you have a history of heart disease, low blood pressure, or have recently had a heart attack or stroke.
• Liver and kidney disease: Individuals with liver or kidney problems may need to adjust their dosage.
• Neurological disorders: People with seizure disorders or Epilepsy should exercise caution when using this medication since it may reduce seizure tolerance.
• Diabetic Retinopathy: People with Diabetes may be more prone to eye difficulties, and using Sildenafil may worsen this condition in those with Diabetic Retinopathy.

Food interactions 

Following food items can interact with the medication, which may affect its absorption or effectiveness:

• High-fat meals: Fatty meals can hinder medicine's absorption, lowering its efficacy or causing a later start of action.
• Grapefruit or grapefruit juice: Grapefruit and its juice can lead to headaches, dizziness, or low blood pressure.
• Alcohol: Alcohol can lead to dizziness, worsening your condition.

Precautions

The following precautions need to be taken while having Malegra DXT Plus tablets:

• Consult your doctor before using the medicine, especially if you have heart disease, high blood pressure, or liver/kidney problems.
• Malegra DXT Plus is only for men and should not be taken by women or children.
• Do not quit suddenly; always follow your doctor's advice to prevent complications.
• Regularly check your blood pressure, mainly if you have a history of cardiovascular disease.
• The medicine may induce dizziness, so avoid driving or using heavy machinery while taking the medicine.

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• 24/7 customer support for any help you need

FAQs

Is Malegra DXT Plus safe for daily use?

No. Malegra DXT Plus is not generally suggested for everyday use. It is intended for as-needed use in treating ED and PE. Daily use may raise the chance of side effects. Always consult your doctor for accurate advice. 

Is Malegra DXT Plus suitable for older men?

Yes. Older men can use Malegra DXT Plus, but caution is advised, especially if you have heart, liver, or renal problems. Before using this medication, a doctor should review your overall health, dose, and interactions. 

What should I do if I miss a dose of Malegra DXT Plus?

If you miss a dosage of the medicine, take it as soon as you remember. If it's almost time for your next dosage, skip the missed dose and stick to your regular dosing plan. Don't double the dosage. 

Is a prescription required to purchase Malegra DXT Plus?

Yes, a prescription is necessary to get the medication, as it contains Sildenafil and Duloxetine, both of which are regulated medications. It's important to consult a doctor to ensure proper usage and avoid potential health risks. 

How to store Malegra DXT Plus?

Keep the medicine at room temperature, away from moisture and heat. Keep it cold, dry, and out of reach of children. Avoid storing in the bathroom; always check the expiration date before using.