Krypton Erlotinib 150 Mg Tablet

Medically Reviewed by

Dr. Akanksha Kaushal

Dr. Akanksha, Pharm-D

Dr. Akansha is a licensed Clinical Pharmacologist with extensive expertise in pharmacovigilance, prescription analysis, drug information, and safety. She's a dedicated educator and avid learner. Dr. Akansha also reviews medical content on GoodRxMedicine, ensuring accurate pharmaceutical information is accessible to all.

Written by

Julian Carter

Julian Carter

Julian, an MBA in Pharmaceutical Management, brings a dynamic blend of expertise and impact with his contributions at GoodRxMedicine. His dedication and innovative spirit continue to shape a brighter future in pharmaceutical management.

What is Krypton Erlotinib 150?

Krypton Erlotinib 150 mg is a targeted Cancer therapy used for Non-small cell Lung Cancer (NSCLC) and Pancreatic Cancer. It contains Erlotinib, a Tyrosine Kinase Inhibitor that inhibits the working of specific proteins that promote Cancer cell growth and spread. 

This, in turn, helps to limit tumor development and improve patient outcomes. Krypton Global Health mainly manufactures the medication.

Uses of Krypton Erlotinib 150

Krypton Erlotinib 150 uses include:

• Treats locally progressed or metastatic NSCLC, especially in individuals with specific Epidermal Growth Factor Receptor (EGFR) mutations.
• Used alongside with Gemcitabine tablet to treat advanced Pancreatic Cancer.
• Specifically inhibits the EGFR pathway, slowing or stopping Cancer cell proliferation.
• Can be used as a post-chemotherapy treatment to prevent Cancer development.
• Helps to prolong progression-free survival in individuals with EGFR mutation-positive tumors.

Working and benefits of Erlotinib

Erlotinib being a Tyrosine Kinase Inhibitor (TKI) exclusively targets the Epidermal Growth Factor Receptor (EGFR). EGFR is a protein present on the surface of specific cells that regulates cell growth and division. In some forms of Cancers, including Non-small Cell Lung Cancer (NSCLC) and Pancreatic Cancer, EGFR is hyperactive, resulting in uncontrolled cell proliferation.  

Erlotinib binds to the specific EGFR Tyrosine Kinase's binding site, blocking its activation and inhibiting the downstream signaling flows essential for tumor growth and survival. This inhibition slows disease development, shrinks tumors, and improves survival outcomes in individuals with EGFR mutation-positive tumors.

Erlotinib effectively manages Non-small cell Lung Cancer and Pancreatic Cancer. It serves the following benefits:

• Effective in EGFR-mutant Cancers: Improves response in individuals with EGFR mutations, notably NSCLC.
• Oral administration: Available as a tablet, making it more convenient than intravenous chemotherapy.
• Targeted therapy: Specifically targets Cancer cells, decreasing damage to normal cells and minimizing side effects when compared to standard chemotherapy.
• Enhances survival and quality of life: Helps patients live longer and have a higher quality of life.
• Can be used as maintenance therapy: It helps to halt Cancer development after initial treatment.

Dosage and how to take Krypton Erlotinib 150

Always follow your doctor’s advice while taking Krypton Erlotinib 150. Here are some common usage guidelines:

• Take the tablet 1 hour before or 2 hours after meal.
• Never crush, chew, or break the tablet; swallow it with a full glass of water.
• Drink lots of water to keep yourself hydrated and reduce side effects.
• Take 1 pill once a day or as advised by your doctor.

Side effects

Krypton Erlotinib 150 tablet can lead to some potential side effects, including:

• Cough
• Diarrhea
• Fatigue
• Fever
• Nausea
• Rash

Most side effects tend to be mild and temporary, gradually fading as your body adjusts to the medication. However, consulting a healthcare professional without delay is crucial if they linger or worsen over time. 

Interactions

Certain medications, underlying health conditions, and specific dietary choices can influence the effectiveness of Krypton Erlotinib 150. 

Drug interactions

Knowing the following drug interactions is crucial to ensure their efficacy and minimize adverse effects:

• Blood thinners
• Blood pressure medicines
• Immunosuppressants
• Antibiotics
• Antifungal medicines

The medications mentioned above are not the only ones that interact with Krypton. Consult your doctor for detailed advice.

Disease interactions

Following diseases can interact with the mediation, influencing both its efficacy and safety profile:

• Liver and kidney disease: Individuals with liver or kidney problems should exercise caution, as dosage changes may be required.
• Gastrointestinal disorders: Patients with stomach or intestinal problems should notify their doctor, as these conditions might impair medicine absorption and effectiveness.
• Ocular disorders: Erlotinib should be cautiously administered in individuals with primary Keratitis, Ulcerative Keratitis, or Pink Eye (Conjunctivitis).

Food interactions

When taking Krypton Erlotinib 150, it's essential to be aware of the following food interactions that can affect its effectiveness and safety:

• Grapefruit and its juice: Grapefruit can raise Erlotinib levels in the bloodstream, increasing the possibility of adverse effects, such as Diarrhea, rash, and liver damage.
• High-fat meal: High-fat foods might alter how your body absorbs Erlotinib, thereby worsening unwanted effects.
• Alcohol: Alcohol could worsen liver adverse effects and raise the risk of stomach discomfort.
• Caffeine: These might worsen stomach discomfort, a typical adverse effect of Erlotinib.

Precautions

Here are some necessary precautions to take while using this medication:

• The medicine is not meant for pregnant and breastfeeding women.
• Patients should avoid driving and operating machinery until they fully recover.
• Avoid smoking since it decreases the efficacy of the medication.
• Erlotinib enhances sensitivity to sunlight. To avoid skin reactions, patients should apply sunscreen with a high SPF and wear protective clothes when outside.
• Regular check-ups are required to watch for serious side effects such as chronic Diarrhea, nausea, or respiratory problems.
• Monitor blood sugar frequently as the medication fluctuates in blood glucose levels.

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FAQs

Can I have herbal tea while taking Krypton Erlotinib?

No. It is not advisable to have herbal teas with the medication. Some herbal teas, particularly St. John's Wort, may affect the efficacy of Erlotinib. Always talk to your doctor before using any herbal supplements.

Can I use painkillers while on Erlotinib?

Yes. Mild pain relievers, such as Paracetamol, are generally safe. Still, Non-steroidal Anti-inflammatory Drugs (NSAIDs) like Ibuprofen and Aspirin should be avoided since they increase the risk of gastrointestinal bleeding.

Can I get vaccinations while taking Erlotinib?

No. Live immunizations should be avoided while having the medication, since Erlotinib might damage your immune system. Inactivated immunizations may be safer but talk to your doctor first before considering a treatment.

Can I have surgery while taking Erlotinib?

No. Erlotinib may impair wound healing and raise the risk of bleeding. Please inform your doctor before any operation, as they may recommend halting medication before and after the procedure to avoid difficulties. Always follow the doctor's advice for a safe procedure.

Does Erlotinib alter skin color?

Yes. Erlotinib may cause skin changes such as hyperpigmentation, dryness, or rashes. Some people may experience acne-like outbreaks or an increased sensitivity to sunlight. Using moisturizers and sunscreen can help reduce discomfort. Consult your doctor if your skin reactions worsen.