Ketosteril Tablet

Medically Reviewed by

Dr. Akanksha Kaushal

Dr. Akanksha, Pharm-D

Dr. Akansha is a licensed Clinical Pharmacologist with extensive expertise in pharmacovigilance, prescription analysis, drug information, and safety. She's a dedicated educator and avid learner. Dr. Akansha also reviews medical content on GoodRxMedicine, ensuring accurate pharmaceutical information is accessible to all.

Written by

Julian Carter

Julian Carter

Julian, an MBA in Pharmaceutical Management, brings a dynamic blend of expertise and impact with his contributions at GoodRxMedicine. His dedication and innovative spirit continue to shape a brighter future in pharmaceutical management.

What is a Ketosteril Tablet?

Ketosteril Tablet is a specialized amino acid supplement containing essential Ketoanalogs of amino acids. Manufactured by Fresenius Kabi India Pvt Ltd, this medication belongs to the class of nutritional supplements designed specifically for chronic kidney disease management. 

Each tablet contains a balanced mixture of amino acids called Alpha Ketoanalogue, which helps maintain proper nutrition while reducing nitrogen waste production.

Uses of Ketosteril Tablet

Ketosteril tablets are primarily prescribed for patients with chronic kidney disease (CKD) to prevent and treat uremic symptoms like nausea or fatigue. It is particularly useful in managing protein metabolism in people on a low-protein diet. 

The medication helps delay the progression of kidney disease and reduces the need for early dialysis. It's also beneficial for patients with inherited metabolic disorders affecting protein utilization.

Working and benefits of Ketoanalogs

Ketosteril works by providing essential amino acids in their keto or hydroxy analog forms, which convert to standard amino acids without producing additional nitrogen waste. This unique mechanism helps maintain protein balance while reducing the workload on compromised kidneys. For optimal effects, it is paired with a low-protein diet. 

Key benefits include:

• Reduced nitrogen waste accumulation
• Better protein utilization
• Delayed progression of kidney disease
• Improved nutritional status
• Reduced uremic symptoms
• Kidney function improvement
• Potential delay in dialysis initiation

The medication typically improves biochemical parameters within 3-4 weeks of regular use.

Dosage and how to take Ketosteril Tablet

Always follow your healthcare provider's specific instructions for optimal results.

Important dosing guidelines include:

• Take it thrice a day or as prescribed. 
• Swallow whole with plenty of water. Do not crush, chew, or break the tablet. 
• Take tablets with or without meals. 
• The dose depends on body weight and protein intake. Do not exceed 4-8 tablets a day. 

Side effects

Common Ketosteril Tablet side effects may include:

• Gastrointestinal discomfort
• Nausea
• Constipation
• Metallic taste
• Mild allergic reactions

Most side effects are mild and temporary. Consult a doctor if they persist or worsen.

Interactions

Ketosteril tablets may interact with foods, medicines, and diseases, such as:

Drug Interactions

• Calcium supplements
• Vitamin D preparations
• Phosphate binders
• Aluminum-containing antacids
• Iron supplements

Disease Interactions

Special attention is needed for people with the following:

• Hypercalcemia (high calcium): Ketosteril can worsen the condition by raising calcium levels. 
• Disturbed amino acid metabolism: This condition can interfere with Ketosteril's intended benefits, which rely on proper amino acid processing for its effectiveness.
• Severe liver disease: It can affect drug metabolism and may increase the risk of adverse effects. 
• Metabolic disorders: People with metabolic disorders may experience altered responses to Ketosteril. 

Food Interactions

Avoid excessive vitamin D-rich food intake and stick to a low-protein diet as prescribed. 

Precautions

Consider the following precautions for the Ketosteril tablet.

• Monitoring of calcium and phosphate levels is required. 
• Strict adherence to a prescribed low-protein diet is essential. 
• Monitor serum electrolytes regularly. 
• Not a substitute for dialysis when indicated. 
• Inform the doctor about pregnancy or breastfeeding plans. 
• Keep regular follow-ups for dose adjustments. 

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FAQs

Are there any contraindications for using Ketosteril Tablet?

Yes, Ketosteril is contraindicated in people with hypercalcemia, disturbed amino acid metabolism, and severe liver disease. It should also be used with caution in patients with a history of kidney stones or elevated calcium levels.

How long should I continue using Ketosteril Tablet?

The duration of Ketosteril treatment varies depending on your kidney function and overall health status. Most patients need to continue treatment long-term as part of their kidney disease management plan. Regular monitoring and follow-ups with your healthcare provider will determine the appropriate duration.

What should I do if I miss a dose of Ketosteril Tablet?

If the missed dose is within 2 hours of your regular dosing time, take it as soon as you remember. If it's closer to your next scheduled dose, leave the missed one and continue with the regular schedule. Never double the dose to make up for a missed one.

Can Ketosteril be used as a protein supplement in healthy individuals?

No, Ketosteril is specifically designed for patients with kidney disease and should not be used as a general protein supplement. It's a prescription medication that requires regular monitoring and should only be taken under medical supervision.

Does Ketosteril interact with common blood pressure medications?

Generally, Ketosteril is safe to take with most blood pressure medications. However, if you're taking ACE inhibitors or ARBs, your doctor may need to monitor your potassium levels more closely. Always inform the healthcare expert about all medications you're taking.