Effectively manages blood sugar levels
FDA-approved active ingredient, Sitagliptin
Treats Type 2 Diabetes Mellitus in adults
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Januvia 100 mg is an antidiabetic medication that treats Type 2 Diabetes Mellitus in adults. It contains an FDA-approved active ingredient, Sitagliptin (100 mg), that effectively manages blood sugar levels in these patients.
The medication belongs to the drug class known as Dipeptidyl Peptidase-4 (DPP-4) Inhibitors. MSD Pharmaceuticals Ltd manufactures the product.
The medication is either prescribed alone or with other Diabetes medications. Taking the medicine alongside diet and exercise can lead to better results.
Januvia 100 mg is primarily used in addition to diet and exercise to manage stable blood sugar levels in patients, particularly adults with Type 2 Diabetes Mellitus. Its primary purpose is to help regulate glucose (sugar) levels by raising insulin release and decreasing glucagon production after meals.
As a secondary use, Januvia may be prescribed with other antidiabetic medications, such as metformin or thiazolidinediones, when single-agent therapy does not provide adequate glycemic control.
Sitagliptin, Januvia's active ingredient, works by inhibiting the DPP-4 enzyme, which boosts and extends the effect of incretin hormones. It leads to increased insulin release after meals and reduced glucose production by the liver, helping to lower and maintain stable blood sugar levels.
Sitagliptin works glucose-dependently, boosting insulin release and reducing glucagon levels only when blood sugar is high. It reduces the risk of Hypoglycemia (low blood sugar levels) compared to other diabetes drugs. Its targeted action helps improve blood sugar control, lower HbA1c levels and carries a lower risk of weight gain and low blood sugar.
Some key benefits include:
Helps normalize defective insulin and glucose regulation
Effectively lowers blood sugar levels
Convenient dosage, usually once a day, makes it easy to incorporate into one's life
Reduces the risk of Diabetes-related complications
Generally well-tolerated medication with low chances of severe side effects
These benefits make Sitagliptin a valuable option for managing Type 2 Diabetes Mellitus.
It is a prescription-based antidiabetic medication that patients should take per the doctor's instructions. Here are some general guidelines on how to take this medication:
Take the dose at a scheduled time daily as directed by your doctor.
Swallow the tablet as a whole with water. Do not chew or crush it.
You can take it with or without food.
Monitor your blood sugar levels regularly.
Though well-tolerated, Januvia may also cause some side effects:
Headache
Sneezing
Sore throat
Stuffy or runny nose
Hypoglycemia (low blood sugar levels)
Stomach ache
These effects subside as the body adjusts to the medication and will not require medical attention. However, consult a doctor if the symptoms continue or worsen.
Januvia can interact with other medicines, health conditions, or specific foods like other antidiabetic medications.
Medications that can interact with Sitagliptin are:
Insulin (antidiabetic medication)
Digoxin (heart medication)
Aspirin (anti-inflammatory medication)
Gatifloxacin (antibiotic medication)
Ketoconazole (antifungal medication)
Ritonavir (anti-HIV medication)
It is not a comprehensive list. Please consult your physician about potential interactions with your current medications.
Taking Januvia 100 mg may not be safe if you have some underlying health issues. In some instances, users need to be extra cautious.
Liver disease: Although generally safe, monitoring is needed for patients with severe liver dysfunction.
Kidney impairment: Possible dose adjustments may be needed for patients with kidney impairment.
Pancreatitis: Close monitoring is required for patients with a history of Pancreatitis.
Heart failure: Caution is advised for patients with a history of heart conditions, with close monitoring and possible dose adjustments.
Avoid consuming these if you are going to take DPP-4 Inhibitor medication, such as Januvia 100 mg:
Alcohol: Alcohol affects the blood glucose level, increasing the chances of getting Hypoglycemia (low blood sugar levels) or Hyperglycemia (high blood sugar levels), depending on your intake.
High-carb foods: Foods high in sugar, refined carbohydrates, and starchy foods can raise the risk of developing high blood sugar levels.
Januvia is not meant for Type 1 Diabetes or Diabetes Ketoacidosis
It is not meant for individuals under 18
Do not take the medication if you are allergic to Sitagliptin
Consult your doctor if you continue to have severe stomach pain.
Pregnant women and breastfeeding mothers should consult their doctor before taking the medication.
Frequent monitoring of blood glucose levels is crucial to ensure the patient's safety.
Maintaining a healthy lifestyle with diet and exercise is necessary for optimal results.
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Exclusive discounts and competitive pricing
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Yes, Januvia is generally considered safe to use long-term for most patients (adults) with Type 2 Diabetes Mellitus, who can tolerate Sitagliptin well with a low frequency of adverse effects. However, close monitoring is essential to ensure the patient's safety.
Januvia 100 mg begins to reduce blood sugar levels within 1 to 2 weeks of starting treatment. However, noticeable improvements in HbA1c and long-term blood sugar control may take up to 24 weeks of regular use.
Yes, you can take Metformin and Januvia together. They are not known to have negative interactions when taken together. Doctors usually prescribe them to promote a stable blood glucose level in Type 2 Diabetes Mellitus patients.
Take the missed dose as soon as possible unless it is time for the next dose. In that case, skip the missed dose and return to your regular schedule. Do not take two doses together to avoid adverse reactions.
No, Januvia is not approved for treating Type 1 Diabetes. The FDA specifies that it should not be used in adults with Type 1 Diabetes or Diabetic Ketoacidosis, as it is ineffective in patients who do not produce insulin.
