Hetrazan 100 Tablet

Medically Reviewed by

Dr. Akanksha Kaushal

Dr. Akanksha, Pharm-D

Dr. Akansha is a licensed Clinical Pharmacologist with extensive expertise in pharmacovigilance, prescription analysis, drug information, and safety. She's a dedicated educator and avid learner. Dr. Akansha also reviews medical content on GoodRxMedicine, ensuring accurate pharmaceutical information is accessible to all.

Written by

Julian Carter

Julian Carter

Julian, an MBA in Pharmaceutical Management, brings a dynamic blend of expertise and impact with his contributions at GoodRxMedicine. His dedication and innovative spirit continue to shape a brighter future in pharmaceutical management.

What is Hetrazan 100 

Hetrazan 100 mg is effective against Filariasis and other worm infections. It contains Diethylcarbamazine Citrate, which belongs to the anti-helminthic class of medications. 

It kills the microfilariae and adult worms and prevents the spread of infection. It effectively eliminates parasites from the bloodstream to reduce the infection symptoms.  

Pfizer Ltd. is the renowned manufacturer and marketer of this Diethylcarbamazine medication.  

Uses of Hetrazan 100 

Hetrazan 100 tablet is an antiparasitic treatment that helps to manage conditions caused by worms. It is used to treat: 

• Filariasis: An infection caused by thread-like parasitic roundworms transmitted by mosquito bites. It treats Lymphatic Filariasis caused by parasites such as Wuchereria Bancrofti and Brugia Malayi. It acts against the parasites' adult and young forms to prevent the infection from spreading. 
• Loiasis: It is caused by Loa loa (eye worm), which affects the skin and eyes. 
• Tropical Pulmonary Eosinophilia: A rare condition caused by an overreactive immune response to microfilaria trapped in the lungs.
• Onchocerciasis (river blindness): Caused by Onchocerca volvulus worm, it is a skin and eye disease. 

Working and Benefits of Diethylcarbamazine

Hetrazan 100 mg tablet contains Diethylcarbamazine (DEC), which effectively targets filarial infection therapy and other worm infections. It disrupts the parasite’s muscle function and metabolic processes, weakening them against the body’s immune response.

DEC helps the immune system recognize and act against microfilariae (young parasites) and inhibits their ability to move independently. Additionally, DEC stimulates phagocytosis, a mechanism where immune cells engulf and destroy parasites.

The key benefits of Diethylcarbamazine Citrate in parasitic disease management include:

• Effectively eliminates parasites: Kills adult worms and microfilariae to prevent the disease progression.
• Treating parasitic and other worm infections: Treats infections caused by parasites and other worms like roundworms. 
• Reduction of symptoms: Helps manage symptoms like swelling and skin irritation caused by filarial infections.
• Rapid action: Works quickly within the body to prevent the spread of infection.
• Prevents disease complications: Reduces the risk of chronic lymphatic damage, such as elephantiasis. Elephantiasis causes the arms and legs to swell and the skin to become stiff and thick, like an elephant's. 

Dosage and how to take Hetrazan 100 tablet

Here's how to take Hetrazan 100 mg tablet dosage safely and effectively:

• Take the tablet precisely as your doctor prescribes at a fixed time each day for consistent results.
• Swallow the tablet without crushing, chewing, or breaking it, which can affect how the medication works. 
• Take Hetrazan with food to reduce the risk of stomach discomfort and enhance absorption.
• Take 2-3 tablets daily or as your doctor directs. Do not exceed the recommended dose. 

It is a prescription-based medication; hence, always consult a doctor before using it.

Side effects

Just like other medicines, Hetrazan tablets can cause some side effects. These include: 

• Itching
• Swelling
• Headache
• Nausea
• Weakness

These Hetrazan 100 side effects usually subside as your body adjusts to the dosage. However, consult a professional for further guidance if they persist or worsen. 

Interactions

Like most ED medications, Hetrazan 100 may interact with other medicines you may take, your health conditions, or specific food or drinks.

Drug interactions

The following medicines can interact with Diethylcarbamazine medicine: 

• Antihistamines (e.g., Cetirizine, Diphenhydramine): They may increase the potential side effects such as drowsiness. 
• Steroids (e.g., Prednisolone): It can affect the effectiveness of Hetrazan 100.
• Blood thinners (e.g., Warfarin): These may increase the risk of bleeding so dose adjustments may be needed. 
• Other antiparasitic drugs (e.g., Ivermectin, Albendazole): If used in combination, it can increase side effects.
• Immunosuppressants (e.g., Closporine): When taken with Hetrazan, it may reduce the body's ability to fight infections.

Hence, tell your doctor about all your medications to avoid any potential interactions. 

Disease interactions

Individuals with the following conditions should use Hetrazan tablets with caution:

• Severe renal impairment 
• Liver conditions
• Asthma or lung conditions
• Heart conditions
• High blood pressure (Hypertension)

Tell your healthcare professional about your medical condition before starting Hetrazan’s treatment for optimum results. 

Food interactions

Individuals must take note of these dietary restrictions before starting Hetrazan tablet treatment. 

• Alcohol: Taking Diethylcarbamazine and alcohol together can intensify side effects.
• Balanced diet: Maintain a balanced diet to support the immune system further and boost recovery from parasitic infections. 

Always follow your healthcare professional’s guidance about food interactions to ensure the efficacy of this medicine. 

Precautions

Individuals planning to take this medication must take note of the following: 

• Avoid taking Hetrazan 100 tablets if you are pregnant or planning to conceive. 
• Consult your doctor if you are breastfeeding, as its effect on the baby has not been well-studied. 
• Individuals with liver or kidney conditions must take this Hetrazan medication under medical supervision as it can increase the risk of side effects. 
• Avoid using Hetrazan tablets if you are allergic to Diethylcarbamazine or its components.
• Use Hetrazan with caution if you have heart problems, which may cause dizziness or irregular heart rhythms.

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FAQs

Is Hetrazan used for Eosinophilia?

Yes, Hetrazan treats Eosinophilia (a condition caused by too many Eosinophils), specifically Tropical Pulmonary Eosinophilia. It kills the parasites that increase Eosinophil (a type of white blood cell) levels. As Hetrazan tablets eliminate the parasites, they modify the immune response and reduce the Eosinophil count to improve symptoms.  

How to store Hetrazan tablets?

To store Hetrazan safely, keep them in their original container, keeping them tightly closed. Store at room temperature, away from moisture, heat, and direct sunlight. Keep it out of reach of children and pets. 

Should I take corticosteroids with Hetrazan 100 for river blindness?

Yes, your doctor can prescribe corticosteroids with Hetrazan for patients with river blindness in some cases. It reduces the inflammation caused by the death of the worms. Always follow your healthcare provider's advice to avoid any risk of potential side effects. 

Can I use Hetrazan tablets long-term?

No, it is not intended for long-term use. Prolonged treatment can lead to serious side effects, including vision problems such as tunnel vision, night blindness, or vision loss. Always take the medicine at the dose and duration advised by your doctor. 

How long is the typical treatment duration with Hetrazan tablet?

The duration of treatment with Hetrazan tablets depends on the type and severity of the infection. Treatment for Lymphatic Filariasis typically lasts 12 days. Hence, always follow your healthcare provider’s instructions and complete the prescribed treatment duration for optimum results.