Fillif 300 Mcg Injection

Medically Reviewed by

Dr. Akanksha Kaushal

Dr. Akanksha, Pharm-D

Dr. Akansha is a licensed Clinical Pharmacologist with extensive expertise in pharmacovigilance, prescription analysis, drug information, and safety. She's a dedicated educator and avid learner. Dr. Akansha also reviews medical content on GoodRxMedicine, ensuring accurate pharmaceutical information is accessible to all.

Written by

Julian Carter

Julian Carter

Julian, an MBA in Pharmaceutical Management, brings a dynamic blend of expertise and impact with his contributions at GoodRxMedicine. His dedication and innovative spirit continue to shape a brighter future in pharmaceutical management.

What is Fillif 300 Mcg injection

Fillif 300 Mcg Injection contains the active ingredient Filgrastim which is a recombinant human Granulocyte Colony-Stimulating Factor (G-CSF). It is used primarily to increase white blood cell production in patients undergoing Chemotherapy. It stimulates bone marrow production for those with certain bone marrow disorders.

Filgrastim works by stimulating the production of neutrophils (a type of white blood cell), helping to reduce the risk of infections associated with neutropenia. It is manufactured by Torrent Pharmaceuticals Limited in WHO-certified facilities.

Uses of Fillif 300 Mcg injection

Fillif 300 Mcg reduces infection risk and is used to treat conditions such as:

• Neutropenia caused by chemotherapy.
• Bone marrow disorders such as Aplastic Anemia.
• Thrombocytopenia (low platelets).
• Chronic neutropenia associated with conditions like Congenital Neutropenia or Idiopathic Neutropenia.
• Post-surgical recovery when low white blood cell count is a concern.
• Stem cell transplant support to prevent infection risk post-treatment.
• In some cases, it is recommended for individuals who have been exposed to high doses of radiation to help regenerate white blood cells. 

Working and benefits of Filgrastim

Filgrastim, the active ingredient in Fillif 300 injection, belongs to the Granulocyte Colony-Stimulating Factor (G-CSF) class of medicines. It functions by making the bone marrow to produce more neutrophils which is a type of white blood cell needed for fighting infections. 

When a person undergoes chemotherapy or suffers from certain medical conditions, their white blood cell count drops, making them vulnerable to infections. Filgrastim helps restore these cells, ensuring the body can defend itself against bacteria and other harmful microorganisms.

One of Filgrastim's biggest advantages is its quick action. It begins working within 24 hours of administration. This rapid response significantly reduces the duration of Neutropenia, lowering the risk of hospitalization due to infections. 

It is widely used in Oncology, Hematology, and transplant medicine, making it important for patients with compromised immunity. By enhancing the body’s ability to produce neutrophils, Filgrastim plays a crucial role in improving survival rates and overall quality of life in individuals undergoing intensive treatments.

Dosage and how to use Fillif 300 Mcg injection

This injection should be administered by a doctor in a hospital only. Some general guidelines on how to use Fillif 300 Injection safely are:

• To be administered as prescribed by your doctor, typically once a day.
• It is injected under the skin (subcutaneously) by a doctor or medical expert.
• Do not self-administer. Follow your doctor's instructions for the injection site and dosage schedule.
• Usually administered daily or as per treatment protocol.

Side effects

Though generally well tolerated, Fillif 300 Injection may sometimes cause side effects, such as:

• Bone pain
• Nausea
• Headache
• Fatigue
• Fever
• Muscle or joint pain

These side effects are often mild and temporary. They usually subside as you adjust to the medicine however, if they persist or worsen, consult your healthcare provider.

Interactions

Before using Fillif 300 Mcg injection, it is important to be aware of its possible interactions with other medications, food and health conditions. 

Drug interactions

Certain drugs may interact with Filgrastim and alter its effectiveness:

• Chemotherapy agents: Since chemotherapy itself reduces white blood cell production, combining it with Filgrastim requires careful dosage adjustments to prevent overstimulation of bone marrow.
• Immunosuppressants: These medicines are used to suppress the immune system, and using them together with Filgrastim may lead to unpredictable results, requiring close medical supervision.
• Liver or kidney problems: In case of people with liver or kidney issues, this injection can be used safely if prescribed by a doctor.

Disease interactions

Certain medical conditions may impact the use of Fillif 300 Injection:

• Bone marrow disorders: Use cautiously if you have underlying bone marrow issues, as Filgrastim directly affects bone marrow activity and may worsen some conditions.
• Allergic reactions: Caution is advised if you have a history of allergic reactions to Filgrastim or similar medications, as severe hypersensitivity reactions can occur.

Food interactions

There are no specific food interactions with Fillif 300 injection. However, maintaining a nutrient-rich diet can support the immune system during treatment. 

• Alcohol: Always consult your doctor before drinking alcohol when undergoing this treatment.

Precautions

Before using Fillif 300 Injection, it is essential to follow specific safety measures to avoid complications. 

• Not suitable for individuals with severe bone marrow disorders unless prescribed by a specialist.
• Pregnant or breastfeeding women should always consult their doctor before using Filgrastim, as its effects on fetal development and lactation are not well established.
• Avoid using Fillif Mcg Injection if you have a history of allergic reactions to Filgrastim or similar medications.
• Monitor white blood cell counts regularly, as excessive production can lead to complications such as spleen enlargement.
• Individuals undergoing chemotherapy should follow their doctor's recommended dosage, as improper use may increase toxicity risks.

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FAQs

Can I drive a car or bike after taking Fillif 300 mcg injection?

No, Fillif 300 mcg injection may cause dizziness, fatigue, or low blood pressure in some people. If you experience these side effects, avoid driving or using heavy machinery. It is best to see how your body reacts before driving.

I am suffering from spleen disease. Can I take Fillif 300 mcg injection?

Patients with spleen disease should use Fillif 300 mcg Injection cautiously, as it may cause spleen enlargement or rupture in rare cases. Consult your doctor to find out if it is safe for you based on your condition.

Does Fillif 300 mcg injection cause haematuria (blood in urine)?

Yes, although Haematuria is not a common side effect of Fillif 300 injection, but in rare cases, it may occur due to increased white blood cell production affecting the kidneys. If you notice blood in your urine, inform your doctor immediately.

Can I take Fillif injection if I have Asthma?

Patients with Asthma should use Fillif injection with caution, as it may cause respiratory side effects like shortness of breath. Consult your doctor before use to assess the risks and take necessary precautions.

I am a patient with a heart problem. Can I take Fillif 300 mcg injection?

If you have a heart condition, inform your doctor before taking Fillif 300 mcg injection, as it may increase the risk of complications like fluid retention or increased heart rate. Your doctor will evaluate whether it is safe for you.