Esperal Tablet

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Dr. Akanksha Kaushal

Dr. Akanksha, Pharm-D

Dr. Akansha is a licensed Clinical Pharmacologist with extensive expertise in pharmacovigilance, prescription analysis, drug information, and safety. She's a dedicated educator and avid learner. Dr. Akansha also reviews medical content on GoodRxMedicine, ensuring accurate pharmaceutical information is accessible to all.

Written by

Julian Carter

Julian Carter

Julian, an MBA in Pharmaceutical Management, brings a dynamic blend of expertise and impact with his contributions at GoodRxMedicine. His dedication and innovative spirit continue to shape a brighter future in pharmaceutical management.

What is an Esperal tablet

Esperal tablet is a prescription medication manufactured by Torrent Pharmaceuticals Ltd. It contains 250 mg of Disulfiram, an aldehyde dehydrogenase inhibitor that helps prevent alcohol consumption.

This medicine is widely used in the treatment of alcohol dependence by causing unpleasant reactions when alcohol is consumed, discouraging further intake.

Esperal works best when combined with counseling and behavioral therapy to achieve long-term alcohol abstinence. This medication should only be taken under medical supervision.

Uses of Esperal tablet

Esperal tablet uses include:

• Treatment of alcohol addiction: Helps individuals overcome alcohol dependence by causing unpleasant reactions when alcohol is consumed.
• Preventing relapse: Supports long-term recovery by discouraging alcohol intake and reducing the risk of relapse.
• Alcohol deterrent therapy: Used as part of a structured program, including behavioral therapy and counseling, to maintain sobriety.

This medication is most effective when combined with psychological support and medical supervision to ensure long-term success in alcohol dependence treatment.

Working and benefits of Disulfiram

Esperal contains Disulfiram, which inhibits aldehyde dehydrogenase, an enzyme that breaks down alcohol in the body. This leads to the accumulation of acetaldehyde, a toxic substance that causes symptoms like flushing, nausea, vomiting, headache, dizziness, and palpitations when alcohol is consumed. By creating these unpleasant reactions, Esperal effectively helps people abstain from drinking.

Key benefits include:

• Discourages alcohol consumption: Produces immediate unpleasant effects upon alcohol intake.
• Supports long-term sobriety: Encourages alcohol abstinence when combined with therapy.
• Fast-acting: Begins working from the very first dose.
• Safe and effective: A well-established treatment for alcohol addiction.

Dosage and how to take Esperal tablet

Follow these instructions to take Esperal safely and effectively:

• Take one tablet daily or as directed by your doctor.
• Swallow the tablet whole with a glass of water; do not chew or crush it.
• It can be taken with or without food, but preferably at the same time each day.
• Do not consume alcohol while taking this medicine.
• If a dose is missed, take it as soon as remembered. However, if it is close to the next dose, skip the missed dose. Do not double-dose.

Consult a healthcare professional before starting or stopping this medication.

Esperal tablet side effects

Most side effects are mild and disappear as the body adjusts. Common Esperal side effects include:

• Headache
• Fatigue
• Drowsiness
• Metallic taste
• Decreased libido

Seek medical help if severe side effects occur.

Interactions

Like all medicines, Esperal may interact with other medications, medical conditions, and certain foods.

Drug interactions

Esperal may interact with the following medications:

• Metronidazole
• Warfarin
• Phenytoin
• Benzodiazepines (e.g., Diazepam, Alprazolam)
• Amitriptyline

Disease interactions

Individuals with the following conditions should use Esperal with caution:

• Liver or kidney disease
• Heart disease or high blood pressure
• Diabetes
• Mental illness or depression
• Seizure disorders

Food Interactions

Avoid consuming alcohol or alcohol-containing products such as:

• Mouthwash, aftershave, cologne, perfumes
• Cough syrups, vinegar, cooking wines
• Certain desserts and over-the-counter medicines

Precautions

Before starting Esperal, it is essential to consider the following:

• Do not consume alcohol while taking the Esperal and for up to 14 days after stopping it.
• Not recommended for individuals under 18 years old.
• Pregnant and breastfeeding women should consult their doctor before using this medication.
• It may cause drowsiness; avoid driving or operating machinery.
• Regular liver function tests may be required.

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FAQs

How does the Esperal tablet work to deter alcohol consumption?

Esperal contains Disulfiram, which inhibits aldehyde dehydrogenase, leading to acetaldehyde buildup when alcohol is consumed. This results in flushing, nausea, dizziness, and palpitations, making alcohol intake highly unpleasant.

Can I consume alcohol while taking an Esperal tablet?

No, consuming alcohol while on Esperal can cause severe reactions such as vomiting, palpitations, dizziness, and low blood pressure. Avoid alcohol during treatment and up to 14 days after stopping the medication.

How long does the Esperal tablet remain effective in the body?

Esperal remains effective for up to 14 days after the last dose. During this period, consuming alcohol can still cause adverse reactions such as nausea, flushing, and palpitations. To avoid complications, it is essential to refrain from alcohol and follow medical guidance carefully.

Does Esperal tablet cure alcohol addiction?

No, Esperal does not cure alcohol addiction. It helps individuals avoid alcohol consumption by making drinking unpleasant. For best results, it should be used alongside behavioral therapy and counseling.

Is Esperal tablet safe for long-term use?

Esperal can be used for long-term alcohol deterrence under strict medical supervision. Regular monitoring of liver function and mental health is necessary, as prolonged use may pose risks such as liver toxicity or psychological effects.