Eporise 40000 IU 1ml Injection

Medically Reviewed by

Dr. Akanksha Kaushal

Dr. Akanksha, Pharm-D

Dr. Akansha is a licensed Clinical Pharmacologist with extensive expertise in pharmacovigilance, prescription analysis, drug information, and safety. She's a dedicated educator and avid learner. Dr. Akansha also reviews medical content on GoodRxMedicine, ensuring accurate pharmaceutical information is accessible to all.

Written by

Julian Carter

Julian Carter

Julian, an MBA in Pharmaceutical Management, brings a dynamic blend of expertise and impact with his contributions at GoodRxMedicine. His dedication and innovative spirit continue to shape a brighter future in pharmaceutical management.

What is Eporise 40000 IU 1ml

Eporise 40000 IU 1ml contains Recombinant Human Erythropoietin Alfa, a blood hormone that stimulates the bone marrow to produce more red blood cells. It is used to treat Anemia caused by chronic diseases, kidney disease, Cancers, bone marrow disorders, and chemotherapy, as well as in patients undergoing major bone surgery.

By encouraging the production of additional red blood cells in the bone marrow, Eporise 40000 helps to correct low blood counts and Anemia, increasing hemoglobin values and reducing the need for blood transfusions.

Eporise 40000 IU is widely manufactured and marketed by Zuventus Healthcare Ltd.

Uses of Eporise 40000 IU 1ml

Eporise 40000 IU 1ml corrects any Dysregulated Erythropoiesis (RBC formation), paving the way for healthy red blood cell production. Clinically, Eporise 40000 Injection causes a direct increase in hemoglobin values and reduces the rates and requirement of blood transfusion.

Eporise 40000 IU Injection is used for various reasons and in a variety of treatments, as follows:

• Chronic kidney disease (CKD): Treats Anemia associated with chronic kidney disease (CKD) in adults and children, especially those on dialysis.
• Cancer chemotherapy: Manages Anemia resulting from Cancer treatments, reducing the need for blood transfusions.
• Bone marrow disorders: Addresses Anemia linked to bone marrow disorders like Myelodysplastic syndromes.
• Major surgery preparation: Used to manage Anemia in patients preparing for major bone surgeries, like hip or knee replacements.
• HIV treatment: Helps treat Anemia in patients undergoing antiviral therapy, such as zidovudine.

Working and benefits of Erythropoietin Alfa

Erythropoietin Alfa, similar to the naturally occurring Erythropoietin in the body, stimulates the bone marrow to produce more red blood cells. It binds to Erythropoietin receptors (EPO-R) on red cell progenitor surfaces, triggering signal transduction pathways that promote red blood cells' survival, proliferation, and differentiation.

Ultimately, Erythropoietin Alfa helps to increase red blood cell count, hemoglobin, and hematocrit levels, improving oxygen transport in the body. This action helps manage Anemia and reduces the need for red blood cell transfusions.

Benefits:

• Treats Anemia: Erythropoietin Alfa is effective in treating Anemia, especially in those suffering from chronic kidney illness, Cancer, or those undergoing chemotherapy.
• Reduces transfusion risks: Erythropoietin Alfa helps patients avoid the risks associated with blood transfusions by stimulating red blood cell production.
• Increases red blood cell count: It increases the red blood cell, hemoglobin, and hematocrit count within 10 days, after which the Reticulocyte count rises, usually within 2 to 6 weeks.
• Supports Erythropoiesis: Erythropoietin is essential for erythropoiesis, the red blood cell production process. Without it, definitive erythropoiesis cannot occur.

Dosage and how to take Eporise 40000 IU 1ml

Eporise 40000 IU is prescription-based and should be taken as per a healthcare professional's instructions. The dosage of Eporise 40000 Injection depends on the individual, the condition being treated, and its severity.

However, you can follow a few steps to increase the effectiveness of this medication:

• Your doctor strictly determines the dose, which is adjusted according to body weight and the cause of the Anemia.
• Usually, a medical expert administers it via Injection, either under the skin or into a vein.
• Effectiveness can be increased by taking iron supplements both before and during therapy.
• If you miss a dosage, you should inform your doctor immediately for instructions.

Side effects

Like any medication, Eporise 40000 IU may cause some side effects. These adverse effects are short-term and will go away as your body adjusts. However, consult a healthcare professional if the side effects persist or worsen.

The side effects of using Eporise 40000 Injection are as follows:

• Nausea and Vomiting
• Fever
• Increased Blood Pressure
• Headache
• Tiredness
• Dizziness
• General aches and pains

Interactions

Like most medications, Eporise 40000 Injection​​ may interact with other medicines you take, your health conditions, or specific foods or drinks.

Drug interactions

Eporise 4000 IU can interact with other medications, which may lead to undesirable side effects by reducing its effectiveness. The below-listed medicines listed might affect the effectiveness when taken along with Eporise 40000 Injection:

• Ramipril: Any medicine that lowers high Blood Pressure may show side effects if used with Eporise IU.
• Cyclosporine
• Thalidomide: If these medicines are used together, the risk of clot formation and associated side effects is very high.
• Abemaciclib, Abiraterone, Adagrasib, Afatinib, Aldesleukin, and Denileukin diftitox: The risk or severity of Thrombosis can be increased when Erythropoietin is combined with these ingredients.

Inform your doctor of all medications before receiving the Eporise 40000 Injection.

Disease interactions

Eporise 40000 Injection has notable interactions with various medical conditions:

• Uncontrolled high Blood Pressure: Not recommended if Blood Pressure is not controlled correctly.
• Pure Red Cell Aplasia (PRCA): Contraindicated in patients with PRCA, a condition with reduced or stopped red blood cell production.
• Recent heart attack or stroke: Not recommended for use in patients with a recent heart attack or stroke.
• Hypersensitivity: Should not be used in patients with hypersensitivity to it or any of its components.
• Active Thrombotic Microangiopathy (TMA): Should not be used in patients with active TMA.
• Uncontrolled Seizures: Should not be used in patients with uncontrolled seizures.
• Tumor progression: This may increase the risk of tumor progression in patients with Cancer.
• Seizures: Raises the patient's chance of seizures with CKD.
• Porphyria, Sickle Cell Anemia, and Thalassemia: Administer therapy cautiously in patients with these conditions.
• Heart disease and kidney disease: Individuals suffering from these conditions must refrain from the use of Rpo since this can cause severe adverse effects.

Patients should consult their healthcare provider regarding these interactions and any underlying health conditions before using the Eporise 40000 IU.

Food interactions

Food choices can impact the patient's effectiveness of Eporise 40000 IU​​. Keep these points in mind:

• Caution with alcohol: The interaction of Eporise 40000 IU with alcohol is not well documented, but it is recommended that you limit or avoid drinking when taking this inhaler. Please consult your doctor for personalized advice.

Precautions

Before starting Eporise 40000 Injection, it is essential to consider the following:

• Allergies: Tell your physician if you have an allergy to any of the components of the Eporise 40000 Injection, and proceed with caution if you have a latex allergy.
• Pregnancy and breastfeeding: Before taking it, consult with your doctor. Eporise 40000 Injections during pregnancy or nursing. It may be unsafe to use throughout pregnancy, and whether it is transferred into breast milk is unknown.

Following these precautions assures the patients of the benefits and minimal negative impacts of Eporise 40000 Injection​​ under medical supervision.

Why buy from us

Buying Eporise 40000 IU or other medications from GoodRxMedicine gives various benefits and easy purchasing options. Here are some of the main benefits, such as:

• Discounted prices and exclusive offers
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• 24/7 customer service and support

FAQs

What do you do if you use too much Eporise 40000 IU 1ml Injection?

A healthcare provider administers Eporise 40000 Injection, so an overdose is unlikely. However, you should speak with your physician or nurse right away if you acknowledge any overdose-related symptoms. Overdose symptoms might include fits and high Blood Pressure.

When should Eporise 40000 IU 1ml Injection not be used?

Eporise 40000IU Injection is not recommended for those with a recent heart attack or stroke, severe uncontrolled high Blood Pressure, or pure red cell Aplastic Anemia. Caution is advised for individuals with heart and blood vessel disorders.

Can Eporise 40000 IU 1ml Injection be used in children?

Yes, Eporise 40000 IU Injection can be used in children over one year old to treat Anemia caused by CKD. The effectiveness and side effects are similar to those seen in adults. A pediatrician should determine the dosage.

Can I get an Eporise 40000 IU 1ml Injection over the counter?

No, Eporise 40000 IU Injection requires a valid prescription. A healthcare professional typically injects it intravenously or subcutaneously, but it can be self-administered if advised by a physician. It treats Anemia related to CKD, Cancer chemotherapy, and other conditions.

Can I consume alcohol with Eporise 40000 IU 1ml Injection?

No, it is generally advised to consult your doctor regarding alcohol consumption while using Eporise 40000 IU Injection. Limited information is available on the interaction between alcohol and this medication.