Epofit 10000 IU Injection

Medically Reviewed by

Dr. Akanksha Kaushal

Dr. Akanksha, Pharm-D

Dr. Akansha is a licensed Clinical Pharmacologist with extensive expertise in pharmacovigilance, prescription analysis, drug information, and safety. She's a dedicated educator and avid learner. Dr. Akansha also reviews medical content on GoodRxMedicine, ensuring accurate pharmaceutical information is accessible to all.

Written by

Julian Carter

Julian Carter

Julian, an MBA in Pharmaceutical Management, brings a dynamic blend of expertise and impact with his contributions at GoodRxMedicine. His dedication and innovative spirit continue to shape a brighter future in pharmaceutical management.

What is Epofit 10000

Epofit 10000 IU helps the bone marrow produce more red blood cells. It treats Anemia (a lack of red blood cells), particularly in patients with chronic kidney disease. 

It contains Epoetin Alfa, classified as an Erythropoiesis-stimulating agent (ESA), a hematopoietic growth factor. Epoetin improves hemoglobin levels and stimulates the bone marrow to produce more red blood cells, thus managing Anemia.

Intas Pharmaceuticals Ltd. manufactures this medication. 

Uses of Epofit 10000

Epofit Injection is effective in treating Anemia caused by chronic kidney disease, chemotherapy, or certain other medical conditions. It contains Erythropoietin, which stimulates red blood cell production.

Its primary uses include: 

• Anemia due to chronic kidney disease.
• Anemia in cancer patients undergoing chemotherapy.
• Anemia in HIV patients taking Zidovudine medication.
• Reduces the requirement for blood transfusions during surgery.

Epofit 10000 Injection helps improve hemoglobin levels, reduce fatigue, and enhance patients' overall quality of life.

Working and Benefits of Epoetin Alfa

Epoetin Alfa in Epofit 10000 IU Injection is a recombinant form of Erythropoietin, a red blood cell production hormone. It binds to Erythropoietin receptors on immature red blood cells in the bone marrow. This triggers a chain reaction inside the cell, signaling the cell to start dividing and developing into mature red blood cells. 

This process increases hemoglobin levels to improve oxygen delivery to tissues, which helps reduce fatigue and weakness. This process effectively treats Anemia caused by chronic kidney disease, chemotherapy, or other medical conditions.

The benefits of Epoetin Alfa include:

• Effective Anemia treatment: Restores healthy red blood cell levels.
• Improved oxygen supply: Enhances energy levels and reduces fatigue.
• Reduced need for blood transfusions: Lowers the dependency on external blood sources.
• Better quality of life: Helps patients regain strength and perform daily activities.

By mimicking natural Erythropoietin, this medication becomes a reliable option for experiencing sustained improvements in overall health.

Dosage and how to take Epofit 10000 IU

Epofit 10000 IU is a prescription medication that should be taken as directed by your doctor. Follow these general guidelines to use this injection

• Take the injection as advised by your doctor, typically when you have a low red blood cell count due to Anemia. 
• Take this injection only from a trained healthcare professional. It is given subcutaneously (under the skin) or intravenously (into a vein). Do not self-administer without proper training. 
• Epofit injections can be taken with or without food. It does not significantly affect the effectiveness of this medication. Hence, consult your doctor for personalized advice. 
• The dosage and frequency depend on your medical condition and hemoglobin levels. Do not exceed the recommended dosage. 

Side Effects 

Epofit Injection is generally well-tolerated with everyone. However, in some cases, this can cause side effects. These include: 

• Fever
• Rash
• Nausea
• Muscle spasm
• Injection site irritation

These side effects are temporary and goes away as your body adjusts to the dosage. However, seek medical attention if it persists or worsens. 

Interactions

Like most medications, Epofit can interact with certain medications, specific health conditions, and limited food and drinks. 

Drug interactions

Epofit 10000 IU Injection can interact with several medicines, which can pose the risk of serious side effects. Key drug interactions include:

• Abemaciclib
• Abiraterone
• Aldesleukin
• Chemotherapy agents

This is not an exhaustive list. Hence, tell your doctor about all the medications you are taking. 

Disease interactions

Patients with specific medical conditions should use Epofit cautiously or avoid it altogether. These include: 

• Uncontrolled high blood pressure
• Thrombosis (blood clotting in veins or arteries)
• Severe heart conditions
• Bone marrow disorders

Consult your doctor for personalized advice. 

Food interactions

No specific food interactions have been observed for Epofit injection. In any case, kindly consult your doctor for better guidance. 

Precautions

Before using this injection, it is essential to take note of the following: 

• Inform your doctor if you have any pre-existing liver conditions. 
• Inform your healthcare advisor if you are pregnant, planning to conceive, or breastfeeding, as it may affect your baby. 
• Kidney function tests require regular monitoring during Epofit treatment.
• Do not use this injection if you are allergic to Epoetin Alfa or its components. 
• Inform your doctor about any allergic reactions, such as rash or swelling. 

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FAQs

Are there any dietary restrictions when using Epofit 10000 IU injection?

No, there are no dietary restrictions while taking this injection. However, to enhance its effect, it is recommended that you stay hydrated and eat iron-rich foods like red meat, beans, and leafy greens. To mitigate its side effects, take smaller portions of meals. 

How long does it take for Epofit 10000 IU Injection to show effects?

Epofit Injection starts working within 2-4 weeks. Initially, immature red blood cells increase within 10 days of treatment. A gradual rise follows in red blood cell count, hemoglobin, and hematocrit. This is usually noticeable within 2-6 weeks, depending on dosage and individual response.

What should I do if I miss a dose of Epofit Injection?

If you miss an Epofit dose, inform your healthcare professional immediately. They will provide instructions about the next steps. It might be skipped to maintain the regular schedule if it's close to your next scheduled dose. Never take a double dose without medical advice.

Can Epofit Injection be used in children?

Yes, Epofit 10000IU Injection can be used in children, but only under a doctor's supervision. It treats Anemia in children over 1 year with chronic kidney disease. Regular monitoring is needed to manage side effects like high blood pressure. Always consult a doctor before use.

When should Epofit 10000IU Injection not be used?

Do not use Epofit 10000IU if the solution appears cloudy, contains floating particles, or has expired. Avoid using it if it has been accidentally frozen or exposed to improper storage conditions, such as a refrigerator failure. Keep it away from children and pets.