Endace 160 Mg Tablet

Medically Reviewed by

Dr. Akanksha Kaushal

Dr. Akanksha, Pharm-D

Dr. Akansha is a licensed Clinical Pharmacologist with extensive expertise in pharmacovigilance, prescription analysis, drug information, and safety. She's a dedicated educator and avid learner. Dr. Akansha also reviews medical content on GoodRxMedicine, ensuring accurate pharmaceutical information is accessible to all.

Written by

Julian Carter

Julian Carter

Julian, an MBA in Pharmaceutical Management, brings a dynamic blend of expertise and impact with his contributions at GoodRxMedicine. His dedication and innovative spirit continue to shape a brighter future in pharmaceutical management.

What is Endace 160​

Endace 160 mg is a medication designed to manage significant weight loss and poor appetite in individuals with chronic illnesses, particularly Cancer. It contains Megestrol, a Progestin-based medication that is an appetite stimulant and promotes weight gain in individuals with Cancer or other conditions leading to severe weight loss. It is classified under the Progestin drug class and affects hormonal balance in the body. 

Manufactured by Samarth Life Sciences, Endace 160 primarily helps in palliative care support for users experiencing Cachexia or Anorexia due to conditions like breast and endometrial Cancer. This medication helps improve quality of life by enhancing body mass and alleviating symptoms associated with advanced Cancer. 

Uses of Endace 160

Endace 160 mg manages conditions associated with severe weight loss and appetite suppression. This medication effectively relieves weight challenges for individuals facing significant chronic conditions, enhancing their overall well-being.

Primary Endace uses include:

• Cancer-related weight loss: Helps individuals regain weight lost due to Cancer and improves body mass in individuals experiencing unintentional weight loss
• Treats Cachexia: Addresses severe muscle wasting and loss of appetite in individuals with advanced Cancer by stimulating appetite
• Hormone-responsive Cancer therapy: Palliative care support in individuals undergoing hormone-responsive Cancer therapy, such as Breast Cancer treatment and Endometrial Cancer therapy
• Manages Anorexia: Assists users with chronic illnesses struggling with appetite loss

Working and benefits of Megestrol

Megestrol Acetate, the active ingredient in Endace 160, is a synthetic Progestin that acts like Progesterone. It stimulates appetite by acting on the hypothalamus, the brain region responsible for hunger regulation. This mechanism helps individuals increase their food intake, improving body mass. Additionally, it interacts with hormone receptors in the body. It affects Estrogen and Androgen receptors, making it useful in hormone-responsive Cancer therapy.

By promoting hormonal regulation, Megestrol is vital in supporting individuals undergoing treatment for hormone-responsive Cancers. It improves quality of life in Cancer patients.

The benefits of Megestrol in Endace 160 include:

• Increased appetite: Megestrol encourages users to eat more. It stimulates appetite in patients with Cancer-related Anorexia/Cachexia, leading to increased food intake.
• Weight gain: Endace helps users regain lost body mass effectively, leading to significant weight gain for some.
• Improved quality of life: Megestrol enhances appetite and promotes weight gain, improving the quality of life for those with chronic illnesses and severe weight loss.
• Relief from symptoms: Endace relieves symptoms of advanced Cancer, providing symptomatic relief as palliative care support.
• Hormonal regulation: Megestrol helps manage hormone-responsive Cancers, such as Breast and Endometrial Cancer. As a synthetic Progesterone, it alters the hormonal balance and may inhibit Cancer growth.
• Palliative care support: Endace improves comfort and nutrition for Cancer patients in palliative care.

Dosage and how to take Endace 160

Consult a healthcare professional before starting Endace 160 Mg tablet dosage. Here’s how to take it effectively:

• Follow your healthcare provider's instructions regarding timing. For optimal effectiveness, take the medication at the same time each day.
• Swallow the tablet whole with a glass of water; do not chew or crush it.
• Take it with food or as directed by your doctor for best results.
• Usually taken once daily or as prescribed by your healthcare provider.

Side effects

While most users tolerate Endace 160 well, some may experience mild side effects as their bodies adjust. Common side effects include:

• Nausea
• Weight gain
• Fluid retention
• Increased appetite
• Mood changes
• Mild dizziness

These Endace 160 mg side effects are typically temporary. However, users should consult their healthcare provider for advice if they persist or worsen.

Interactions

Endace 160 mg may interact with certain medications, health conditions, and foods. Understanding these interactions ensures safe use.

Drug interactions

Individuals on Megestrol must inform their healthcare providers about all medications they are taking to manage possible interactions effectively. Megestrol has some known medicine interactions, including:

• Anticoagulants (Blood thinners)
• Corticosteroids
• Diabetes medications
• Rifampin 
• Anticonvulsants

Disease interactions

Megestrol is associated with some disease interactions that require careful consideration:

• History of Thrombosis: People with a history of blood clots should be cautious because Megestrol increases the risk of blood clots and may worsen clotting problems.
• Liver disease: People with liver problems need dose adjustments when taking Megestrol because severe liver issues affect how the body processes the medication.
• Diabetes: Individuals with Diabetes may require to monitor their blood sugar levels closely, as Megestrol can surge blood sugar levels and worsen Diabetes control.
• Kidney disease: Consult a doctor before using Megestrol if you have a history of kidney disease, as kidney function affects how the medication clears from your system.
• Heart disease: Individuals with heart disease may require close monitoring due to the risk of fluid retention associated with Megestrol use.

Food interaction

Users should avoid excessive alcohol consumption while on this medication, as it may increase the risk of side effects.

Precautions

To ensure safe use of Endace 160, consider the following precautions:

• It is not safe for use in pregnant or breastfeeding women.
• Inform your doctor of any pre-existing liver, kidney, or heart conditions.
• Regular monitoring of blood sugar is necessary for individuals with Diabetes.
• Do not stop taking the medication suddenly without medical advice.
• Keep out of reach of children.
• Store at room temperature, far from moisture and heat.

Why buy from us

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FAQs

Does Endace-160 tablet affect fertility?

No, the Endace-160 tablet does not affect fertility. It may change your menstrual cycle but does not stop you from getting pregnant. Always talk to your doctor about using birth control if you are taking this medicine. 

Is Endace-160 tablet safe for diabetics?

No. People with Diabetes can use the Endace-160 tablet, but it may raise blood sugar levels. You should check your blood sugar often and talk to your doctor if it gets too high. Avoid alcohol while taking this medicine for safety.

Can I stop taking Endace-160 tablet when I feel better?

No, you should not stop taking Endace-160 tablets when you feel better. Always talk to your doctor before stopping this medicine. They will tell you the right time to stop. Stopping suddenly can cause problems. Keep taking it as your doctor advises.

What if I miss my dose?

If you miss a dose of Endace, take it as soon as you remember. If it’s almost time for your next dose, skip the missed one. Don’t take two doses at once. Always follow your doctor’s advice on what to do.

Is Endace-160 tablet safe to be taken during pregnancy?

No, the Endace-160 tablet is not safe to take during pregnancy. It can harm the developing baby. If you are pregnant or planning to become pregnant, talk to your doctor before using Endace. Always follow your doctor's advice for your health and safety.

Does Endace-160 tablet need to be refrigerated?

No, you do not need to refrigerate the Endace-160 tablet. You should store it at room temperature, between 10°C and 30°C. Please keep it away from light and moisture to ensure it stays effective. Always keep it out of reach for children's safety.

Is Endace-160 tablet used for hot flashes?

No, the Endace-160 tablet is not used for hot flashes. It is mainly for helping people with poor appetite and weight loss, especially those with Cancer or AIDS. Always talk to your doctor about the proper treatment for you.