Dpressin Nasal Spray

Medically Reviewed by

Dr. Akanksha Kaushal

Dr. Akanksha, Pharm-D

Dr. Akansha is a licensed Clinical Pharmacologist with extensive expertise in pharmacovigilance, prescription analysis, drug information, and safety. She's a dedicated educator and avid learner. Dr. Akansha also reviews medical content on GoodRxMedicine, ensuring accurate pharmaceutical information is accessible to all.

Written by

Julian Carter

Julian Carter

Julian, an MBA in Pharmaceutical Management, brings a dynamic blend of expertise and impact with his contributions at GoodRxMedicine. His dedication and innovative spirit continue to shape a brighter future in pharmaceutical management.

What is Dpressin Nasal Spray

Dpressin Nasal Spray contains desmopressin as an active salt. It is used to treat central Diabetes Insipidus and is beneficial in treating Nocturnal Enuresis (bedwetting) in children and adults.

It is a synthetic form of Vasopressin, a naturally occurring hormone that balances water levels in the body.

Dpressin Spray​​ is widely manufactured and marketed by United Biotech Pvt. Ltd.

Uses of Dpressin Nasal Spray

Dpressin Nasal Spray containing Desmopressin is a synthetic form of Vasopressin. It is used to treat various conditions:

• Central Cranial Diabetes Insipidus: A condition causing the body to lose too much fluid. Desmopressin replaces a low level of Vasopressin to help control water balance.
• Nocturnal enuresis (bedwetting).
• To manage temporary Polyuria (extreme urination) or Polydipsia (extreme thirst) after head trauma or surgery in the pituitary gland.
• Von Willebrand disease (VWD): It can also help treat mild to moderate VWD by promoting the release of von Willebrand factor, a clotting protein.
• To manage increased thirst and frequent urination caused by specific brain injuries or brain surgeries.
• Adults with Nocturnal Polyuria who wake up twice or more times to urinate at night.

Working and benefits of Desmopressin

Desmopressin is a synthetic form of a natural hormone called Vasopressin, often known as an Antidiuretic Hormone (ADH) or Arginine Vasopressin (AVP). The hypothalamus produces Vasopressin, which is stored in the posterior pituitary gland.

Desmopressin works by binding to V2 receptors in the kidneys, increasing water re-absorption and reducing urine production. It mimics the action of Vasopressin in the patient's body.

Benefits:

• Treats Diabetes insipidus: Desmopressin is used to treat central Diabetes insipidus, a condition where the body struggles to regulate fluid balance.
• Controls bedwetting: It helps manage nocturnal enuresis (bedwetting).
• Manages bleeding: Desmopressin can help control bleeding in mild to moderate hemophilia A and von Willebrand disease cases.
• Reduces excessive urination: It reduces the amount of urine produced, especially in cases of Nocturia (waking up at night to urinate) and Polyuria (excessive urination) caused by certain conditions, head injuries, or brain surgery.

Dosage and how to take Dpressin Nasal Spray

Dpressin Spray is prescription-based and should be taken as per a healthcare professional's instructions.

However, you can follow a few steps to increase the effectiveness of this medication:

• Dosage for adults and children (4 years old and older): The recommended dosage is once daily in one nostril. Follow the prescribed doses carefully.
• How to Use: Remove the protective cap. Blow your nose. Tilt your head backward slightly and carefully insert the nozzle into one nostril in a standing or sitting position. Hold your breath and press the spray once. Use alternative nostrils for each additional dose. Replace the protective cap after using the nozzle and wipe it clean with fresh tissue.
• Do not exceed the recommended number of sprays to prevent unwanted side effects.
• If a dose is missed, don't take the next dose twice to compensate for the missed one.

Side effects

Like any medication, Dpressin Spray may cause some side effects. These adverse effects are temporary and will subside as your body adjusts. However, consult a healthcare professional if the side effects persist or worsen.

The side effects of using Dpressin Spray​​ are as follows:

• Nasal discomfort
• Inflammation of the throat and nasal passages
• Sneezing
• Headache
• Nausea
• Cough
• Nosebleeds

Interactions

Dpressin Spray​​ may interact with other medicines you take, your health conditions, or specific foods or drinks like most medications.

Drug interactions

The below-listed medicines listed might affect the effectiveness when taken along with Dpressin Spray:

• Tricyclic antidepressants and Selective Serotonin Reuptake Inhibitors (SSRIs): These medications, used to treat depression, can interact with nasal Desmopressin.
• Opiates: Pain medications like oxycodone, hydrocodone, and morphine may interact with Desmopressin.
• Nonsteroidal anti-inflammatory drugs (NSAIDs): Medicines like iBuprofen and Naproxen, found in many over-the-counter products for pain, swelling, and fever, can interact with Desmopressin.
• Lamotrigine and Carbamazepine: These medicines, used to treat seizures, may interact with Desmopressin.
• Oxybutynin: Used to treat overactive bladder, this medication can interact with Desmopressin.
• Medicines that increase blood pressure: Pseudoephedrine, found in many over-the-counter cold and allergy products, can interact with Desmopressin.
• Sulfonylureas: Chlorpropamide, a medicine used to treat Diabetes, may interact with Desmopressin.
• Corticosteroids: Medicines for inflammatory conditions, Asthma, or COPD can interact with Desmopressin.
• Diuretics: Also called water pills, these medicines are used to reduce fluid retention and blood pressure, and they can interact with Desmopressin.

To avoid potential drug interactions, tell your doctor about all of your prescription medicines, supplements, herbal products, and supplements you are taking.

Disease interactions

Here are the disease interactions to be aware of when using Dpressin Spray:

• Kidney disease: Be cautious when used in patients with severe kidney disease.
• Hyponatremia: Avoid using this spray for patients with Hyponatremia (low sodium levels in the body).
• Fluid retention: Use caution in individuals with a history of excessive fluid intake or fluid retention.
• Heart conditions: Exercise caution in patients with high blood pressure or heart failure.
• Nasal issues: Use cautiously if the nasal lining has swelling or scarring.
• Fluid/mineral imbalance: Be careful if you have illnesses causing fluid or mineral imbalances, such as Cystic Fibrosis.

Before taking the Dpressin spray, patients should discuss these interactions and any underlying medical conditions with their doctors.

Food interactions

Food choices can impact the effectiveness of the Dpressin Spray for the patient. Keep these points in mind:

• Fluid intake: Avoid consuming excessive fluids while using D-Pressin Nasal Spray, as this can lead to water buildup in the body.
• Caution with alcohol: Alcohol consumption may interfere with how D-Pressin Nasal Spray works, so it's best to limit or avoid it. It's also unknown if alcohol affects nasal Desmopressin.

Precautions

Before starting Dpressin Spray, it is essential to consider the following:

• Pregnancy and breastfeeding: Pregnant and breastfeeding women should consult their doctor before using this medication.
• Administration: Administer Dpressin Spray for intranasal use only.

Following these precautions assures the patients of the benefits and minimal negative impacts of the Dpressin Spray​​ under medical supervision.

Why buy from us

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• Exclusive discounts with the lowest price
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• Positive customer reviews and reliable quality
• Availability of substitute medicines with the same active ingredients

FAQs

How long do I need to give Dpressin Nasal Spray to my child for bedwetting?

Doctors generally prescribe Dpressin Spray for 3 months to treat bedwetting. After this period, the doctor may stop the medicine for a week to see if it is still needed.

Does Dpressin Nasal Spray cure bedwetting?

No, Dpressin Spray does not cure bedwetting but helps control it. It replaces a hormone, Vasopressin, to balance water and salt levels, reducing the urge to urinate. Dpressin reduces bedwetting during treatment, but many children start wetting again when treatment stops.

Does Dpressin Nasal Spray make you gain weight?

Yes, as Dpressin Spray may lead to fluid overload, which can cause weight gain. Fluid overload is a profound side effect, and you should contact your doctor if you experience related symptoms. The medication itself doesn't directly cause weight gain.

What if you forget to take Dpressin Nasal Spray?

If you miss a dose of Dpressin Spray, take it as soon as you remember. When it's almost time for your next dose, skip the missed one and return to your regular routine. Do not use a double dose to make up for the missed one.

Are there any risks associated with missing a dose of Dpressin Nasal Spray?

No, as per clinical studies, there is no risk associated with missing any dose of Dpressin spray. However, if you miss a dose of Dpressin Spray, use it as soon as you remember, as per your doctor's prescription.