Darbecure 25 mcg Injection

Medically Reviewed by

Dr. Akanksha Kaushal

Dr. Akanksha, Pharm-D

Dr. Akansha is a licensed Clinical Pharmacologist with extensive expertise in pharmacovigilance, prescription analysis, drug information, and safety. She's a dedicated educator and avid learner. Dr. Akansha also reviews medical content on GoodRxMedicine, ensuring accurate pharmaceutical information is accessible to all.

Written by

Julian Carter

Julian Carter

Julian, an MBA in Pharmaceutical Management, brings a dynamic blend of expertise and impact with his contributions at GoodRxMedicine. His dedication and innovative spirit continue to shape a brighter future in pharmaceutical management.

What is Darbecure 25

Darbecure 25 is a medication designed to treat Anemia with Chronic Kidney Disease (CKD). It contains Darbepoetin alfa, a synthetic form of the naturally occurring hormone erythropoietin, which helps in the production of red blood cells.

Darbecure is approved by the FDA for use in both CKD patients and Cancer patients for Chemotherapy-related Anemia, helping improve their quality of life by alleviating the symptoms of Anemia. It is manufactured by Emmcure Pharmaceuticals Limited in WHO-certified facilities.  

Uses of Darbecure 25

Darbecure is used for Anemia treatment in patients with CKD. Anemia is a common condition in CKD patients because the kidneys lose their ability to produce erythropoietin. 

Darbecure stimulates red blood cell production, thus reducing the risk of complications related to Anemia, such as fatigue, weakness, and the need for blood transfusions. Darbecure is also used in patients undergoing chemotherapy to treat anemia caused by Cancer treatments. 

Working and benefits of Darbepoetin

Darbepoetin alfa, the active ingredient in Darbecure 25, is a long-acting synthetic version of erythropoietin, a hormone that naturally regulates the production of red blood cells in the bone marrow. Darbecure helps by regulating the bone marrow to produce more red blood cells. This improves the oxygen-carrying capacity of the blood. 

By improving red blood cell production, it helps maintain energy levels and prevent further complications from low hemoglobin, making it an essential medication for individuals with Anemia due to CKD or Chemotherapy.

• The medication works slowly but steadily, with noticeable improvements often occurring within 1-2 weeks of starting treatment. 
• For patients undergoing chemotherapy, it can reduce the need for blood transfusions, lower the risk of infection, and improve overall quality of life. 
• The medication also has a long-acting formulation, which means it can be administered less frequently than other similar treatments, offering convenience to the patient. 
• Additionally, by promoting red blood cell production, Darbecure may help reduce symptoms such as dizziness, shortness of breath, and heart strain that are commonly associated with Anemia.

Dosage and how to take Darbecure 25

Darbecure should be administered in medical settings only. Some general guidelines for its use are as follows: 

• Darbecure by a healthcare provider in a medical setting. The typical dosage schedule is based on your physician's recommendations and your individual treatment plan.
• It is administered intravenously (into the vein) or under the skin by a doctor or nurse. 
• Do not self-administer. Regular monitoring will be necessary during treatment.
• Do not exceed the prescribed dosage. Always follow your doctor’s instructions for the best results.

Side effects

While Darbecure is generally well-tolerated, some may experience mild side effects. The common Darbecure 25 mcg injection side effects include:

• Headache
• Fatigue
• Dizziness
• Nausea
• Injection site pain
• Cough
• Joint pain

Most side effects are mild and tend to subside as the body adjusts. If any severe side effects occur, consult a healthcare professional immediately.

Interactions

Being aware of these interactions helps in avoiding complications and ensures the medication works effectively.

Drug interactions

Darbepoetin alfa may interact with certain medications. Inform your doctor about all the medicines you take, including:

• Antihypertensive medications: It may cause low Blood Pressure when taken with Darbecure 25. Regular monitoring is essential.
• Iron supplements: Dosage adjustments may be required, as iron supports red blood cell production along with Darbecure.
• Other erythropoiesis-stimulating agents: Taking multiple agents can lead to excessive red blood cell production, increasing health risks.

Disease interactions

Some health conditions can impact the way Darbecure works in the body. Take precautions if you have:

• Heart disease: This medication can put extra strain on the heart, so patients with heart conditions should use it cautiously.
• Allergies: Report any past allergic reactions to your doctor before starting Darbecure 25 to prevent complications.
• Liver disease: Inform your doctor about your liver issues before taking this injection.
• Kidney problems: This injection is safe for use in people with kidney problems if prescribed by a doctor.

Food interactions

No major food interactions are known with Darbecure. However, consult your doctor about any dietary restrictions while using this medication. Keep in mind the following: 

• Alcohol consumption: Drinking alcohol while on Darbecure may affect Blood Pressure and overall treatment effectiveness. 

Precautions

Before using Darbecure, it is essential to follow safety measures to ensure proper usage and minimize risks. 

• It is not recommended for individuals under 18 years 
• Pregnant and breastfeeding women must consult their doctor before using Darbecure, as its effects during pregnancy and lactation are not well studied.
• Darbecure 25 may put extra strain on the heart, so individuals with a history of heart disease should use it under medical supervision.
• If you have experienced allergic reactions earlier to similar medicines, avoid using Darbecure.
• Inform your doctor about ongoing medication.

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FAQs

Does Darbecure 25 mcg injection cause high Blood Pressure?

Yes, Darbecure may cause high Blood Pressure in some individuals. If you have a history of hypertension or observe a rise in your Blood Pressure levels during treatment, consult your doctor for monitoring and management.

Can Darbecure 25 mcg Injection be used in children?

No, Darbecure is primarily prescribed for adults, and its safety in children has not been well-established. It should only be used in pediatric patients if specifically recommended by a doctor based on medical necessity.

I have high blood sugar, should I tell it to a doctor before taking Darbecure 25 mcg Injection?

Yes, it is important to inform your doctor about high blood sugar levels before using Darbecure. The medication may impact blood sugar regulation, so your doctor will assess potential risks and adjust your treatment plan if needed.

Can I stop using Darbecure once my symptoms improve?

No, you should not stop using Darbecure without consulting your doctor. Stopping suddenly may lead to a drop in red blood cells in the body, increasing the risk of Anemia.

Does Darbecure increase the risk of blood clots?

Yes, Darbecure may increase the risk of blood clots in some individuals. If you experience symptoms like swelling, chest pain, or difficulty breathing, seek medical help immediately.