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Ashwagandha Side Effects and Medication Interactions: What to Watch For

Julian Carter
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Ashwagandha side effects: How dangerous are they?

Ashwagandha is a powerful adaptogenic herb widely used in Ayurvedic medicine. It has gained popularity for its potential to reduce stress, enhance mental clarity, and improve physical performance. 

While Ashwagandha is generally considered safe, it’s essential to understand its common and rare side effects. Additionally, knowing how this supplement might interact with other medications is crucial for maximizing its benefits and minimizing potential risks. 

In this blog, we’ll explore the Ashwagandha side effects and how they interact with medications and offer tips on reducing unwanted effects.

Common side effects of Ashwagandha

Ashwagandha is well tolerated, but some users may experience mild side effects. These effects are typically short-lived and decline as the body adjusts to the supplement. The common side effects of Ashwagandha include:

Digestive discomfort:

Some individuals may experience Nausea, upset stomach, or Diarrhea after taking Ashwagandha, especially if consumed on an empty stomach. Taking it with food can help reduce the chances of digestive issues.

Drowsiness or sedation:

Due to its calming properties, Ashwagandha may cause drowsiness, especially when taken in higher doses. This can be beneficial for those looking to manage stress or improve sleep but may be unwanted during the day when alertness is needed.

Headache:

Some people report headaches when first starting Ashwagandha, although this tends to diminish over time as the body becomes accustomed to the herb.

Dry mouth:

A less common but notable side effect is dry mouth, possibly due to Ashwagandha’s impact on salivary glands.

Rare and serious side effects of Ashwagandha

Though Ashwagandha has many benefits and is considered safe for most people, rare but serious side effects can occur. These are typically associated with high doses or prolonged use, and it’s always wise to consult a healthcare professional before starting any supplement, especially if you have pre-existing conditions.

Allergic reactions:

In rare cases, individuals may experience allergic reactions to Ashwagandha, which could manifest as hives, swelling, or difficulty breathing. If any of these symptoms occur, it’s essential to discontinue use and seek medical attention immediately.

Liver toxicity:

Although extremely rare, some reports have linked high doses of Ashwagandha to liver toxicity. This is particularly true in individuals who are already taking medications that affect liver function. However, in most cases, Ashwagandha does not pose a risk to liver health.

Hormonal effects:

Ashwagandha may influence thyroid hormone levels, leading to either an increase or decrease in thyroid activity. For those with thyroid disorders, it’s critical to monitor hormone levels regularly while using this supplement.

Lower blood sugar and blood pressure:

Ashwagandha may lower blood sugar and blood pressure, which is typically a positive effect for those with high levels of either. However, if you’re on medication to manage blood sugar or blood pressure, this can lead to dangerously low levels. Monitoring levels with your doctor can help prevent complications.

Fact:
The word “Ashwagandha” means “smell of horse” in Sanskrit, reflecting both its strong smell and the belief that it imparts the strength and vitality of a horse.

Ashwagandha side effects for females and males

While the general side effects of Ashwagandha apply to both genders, there are some nuances to consider based on hormonal and physiological differences. Females may experience changes in their menstrual cycle or hormonal balance, particularly if they have existing hormonal conditions like PCOS. For males, Ashwagandha may boost testosterone levels, which is beneficial for many but could be problematic for those with hormone-sensitive conditions.

Ashwagandha’s interaction with other medication

Ashwagandha may cause low Blood Sugar
Ashwagandha may cause low Blood Sugar

Ashwagandha can interact with certain medications, particularly those that affect blood sugar, blood pressure, and immune function. Understanding these interactions is vital for those who take prescription medications.

  1. Medications for diabetes: Since Ashwagandha can lower blood sugar, combining it with diabetes medications may result in hypoglycemia (low blood sugar). It’s important to monitor your blood sugar levels and consult a doctor before using Ashwagandha alongside diabetes medications.
  1. Blood pressure medications: Ashwagandha’s ability to lower blood pressure can enhance the effects of blood pressure-lowering medications. While this is typically a positive outcome, it could lead to blood pressure dropping too low, causing dizziness or fainting. Regular monitoring and dosage adjustments may be necessary.
  1. Thyroid medications: Ashwagandha can influence thyroid function by increasing thyroid hormone levels. If you’re taking thyroid medication, this interaction could cause your thyroid to become overactive, leading to hyperthyroidism. Close monitoring of thyroid function is recommended.
  1. Immunosuppressants: Because Ashwagandha can boost immune function, it may reduce the effectiveness of medications designed to suppress the immune system. This could be an issue for individuals who are on immunosuppressant drugs following organ transplants or for autoimmune conditions.
  1. Sedatives: Ashwagandha has calming properties and may increase the effects of sedative medications. This could result in excessive drowsiness or fatigue, particularly when taken with prescription sleep aids or anti-anxiety medications.
Warning:
Pregnant women should avoid Ashwagandha, as it may cause premature labor or miscarriage.

How to minimize Ashwagandha side effects

While the side effects of Ashwagandha are generally mild, there are several ways to reduce the likelihood of experiencing them. Here are some practical tips to help minimize any unwanted effects:

  • Start with a low dose: Beginning with a lower dose allows your body to adjust to Ashwagandha gradually. You can increase the dosage over time as your body becomes more accustomed to it.
  • Take with food: Consuming Ashwagandha with meals can help prevent digestive discomfort. This is especially helpful for individuals prone to stomach upset when taking supplements.
  • Hydrate well: Drinking plenty of water can help counteract dry mouth and support overall digestive health.
  • Monitor hormone levels: Regularly monitoring hormone levels is crucial if you have thyroid or other hormonal imbalances. Consult your doctor before starting Ashwagandha, especially if you have an existing thyroid condition.

Conclusion

Ashwagandha offers numerous health benefits, from reducing stress and anxiety to enhancing physical performance and improving sleep. While it is generally well-tolerated and side effects are rare, it’s important to be aware of potential issues like digestive discomfort, drowsiness, and medication interactions. Most people find that Ashwagandha’s side effects are mild and easily managed by adjusting the dosage or timing of intake.

The side effects of Ashwagandha are usually not serious for both men and women. However, females may need to be mindful of hormonal changes, and males should be aware of its potential impact on testosterone levels. 

Always consult with a doctor before adding any supplement to your regimen, particularly if you are on medication or have underlying health conditions. Ashwagandha remains a powerful ally for many, and with the right approach, you can enjoy its benefits without worry.

Frequently Asked Questions

Can I take Ashwagandha every day, and for how long?

Yes, When Ashwagandha is taken by mouth, it is safe for everyday use for up to three months. However, you must consult your doctor for long-term use, as it may interact with other medications.

What are the forms I can get Ashwagandha in the market?

Ashwagandha is available in various forms in the market including pills, capsules, powders, and gummies. You can choose the form that best suits your lifestyle and preferences.

Can Ashwagandha cause weight gain or weight loss?

Ashwagandha may help with weight loss by reducing body fat levels and increasing muscle mass. It may also help regulate appetite and promote a healthy metabolism.

Is it safe to take Ashwagandha while on diabetes medication?

No, ashwagandha might not be safe to take while on diabetes medication because it may lower blood sugar levels. This could make it unsafe to use antihyperglycemic (glucose-lowering) medications.

Does Ashwagandha interact with blood pressure medications?

Yes, Ashwagandha may lower blood pressure, potentially intensifying the effects of blood pressure medications, leading to hypotension. Consult a healthcare provider before combining them to avoid adverse interactions or excessively low blood pressure.

Citations:
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