Testosterone gel is a popular type of Testosterone Replacement Therapy (TRT)
It is commonly prescribed to individuals with low testosterone levels.
However, many wonder, “How long does it take for testosterone gel to work?”
Let us explore the answer to the above question and learn more about testosterone gel.
How long does testosterone gel take to work?
Testosterone gel is absorbed through the skin and helps with low testosterone levels by allowing the hormone to enter the bloodstream slowly.
A study states that the gel may take 2-4 hours for proper absorption after application.
Research states that testosterone gels may take three weeks to show effects on libido.
However, it may take six months to notice changes in a person’s erection and ejaculation.
The time period may be different for everyone as several factors affect the working of testosterone gel.
These factors include dosage, consistency of application, and individual testosterone levels.
Higher dosages may give quicker results. However, one must use the medication consistently under a doctor’s instructions.
Also, since everyone is unique, individual testosterone levels and responses may also change the effectiveness and working of the medication.
How to apply testosterone gel?

To apply testosterone gel, first make sure you measure the proper amount of gel.
A study states that the recommended starting dosage is 5g per day of 1% testosterone gel, like Cernos gel 1%.
One should apply testosterone gel early in the morning on dry skin over the shoulders, upper arms, and abdomen.
Patients should wash their hands well before and after applying the gel.
Put clothes over the spot after making sure the medicine is dry, and do not shower or swim for 2-5 hours.
Keep the testosterone medication away from women and children as it may be harmful to them.
Consult a doctor if the current testosterone gel dosage is not working or if you face side effects.
Side effects of testosterone gel

Using testosterone gel may lead to some possible side effects.
The side effects of testosterone gel include:
- Allergic reactions
- Blood clot
- Heart attack
- Increased blood pressure
- Liver injury
- Mood swings
These side effects are normally temporary, but one should consult a doctor if they become persistent.
Always cover the gel area, as there is a risk of skin-to-skin transfer while using testosterone gel.
The gel is not suitable for women, children, and men with healthy testosterone levels.
These people may also experience side effects if they come in contact with the medicine.
Key Takeaways
Testosterone gel is a popular type of Testosterone Replacement Therapy (TRT) used to treat low testosterone levels.
But how long does it take for testosterone gel to work?
Testosterone gels may take three weeks to show effects on libido and six months for erection and ejaculation.
However, the time period may differ for everyone due to dosage, consistency of application, and individual testosterone levels.
Consult a doctor and follow instructions properly to see the best results.
Frequently Asked Questions
What to expect when using testosterone gel?
The testosterone gel starts getting absorbed after 2-4 hours of application. The hormone from the gel starts entering the bloodstream slowly. With constant use, one may notice physical changes like oily skin, acne, increased muscle mass, and more.
Which is the best body part to apply testosterone gel?
One should apply testosterone gel on the upper arm or shoulders. These areas are generally covered by a t-shirt and reduce the risk of transfer.
When is the best time to apply testosterone gel?
One should apply testosterone gel in the morning after showering. The medicine should be used at the same time daily. However, one should wait 2-4 hours if they plan to take a bath after applying the medication.
How long does testosterone gel last?
The Food and Drug Administration (FDA) states that the effectiveness of testosterone gel lasts for 24 hours after application. However, one should cover the area after applying the medicines to prevent transfer to others.
Can women use testosterone gel?
No, women should not take testosterone gel or any other type of Testosterone Replacement Therapy. The research on these medications for women is limited, and it may cause unwanted side effects.
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